Evaluation of blood vessel network formation and visual field defect in optic disc melanocytoma

AimTo investigate the association between visual field defects and blood vessel network (BVN) formation in optic disc melanocytomas (ODMs) using optical coherence tomography angiography (OCTA).MethodsSingle-centre, retrospective case series of 32 eyes of 32 patients with ODM, in which eyes were divided into two groups based on complete and incomplete BVN formations.ResultsOCTA revealed incomplete BVN formation in 16 of 32 ODMs. The location of BVN absence corresponded to the location of hypofluorescence from fluorescein angiography (FA) in 12 (75%) and to the location of visual field defect in 13 (81%) ODMs in the incomplete BVN group. Perimetric indices were significantly worse in the incomplete BVN group than in the complete BVN group. Linear regression of mean deviation (MD) and Visual Field Index (VFI) on the area of BVN absence were statistically significant (p=0.01 and p=0.003, respectively), whereas linear regressions of MD and VFI on the tumour area were not statistically significant (both p=0.09) in the incomplete BVN group.ConclusionThe location of BVN absence within ODMs corresponded to the location of visual field defect and the location of FA hypofluorescence. Visual field defect was more severe in the incomplete BVN group than in the complete BVN group. Visual field defect was more significantly associated with the area of BVN absence than the tumour area.

Download Full-text

Relationship between consecutive deterioration of mean deviation value and progression of visual field defect in open-angle glaucoma

Clinical Ophthalmology ◽

10.2147/opth.s94497 ◽

2015 ◽

pp. 2217 ◽

Cited By ~ 2

Author(s):

Tomoko Naito ◽

Keiji Yoshikawa ◽

Shiro Mizoue ◽

Mami Nanno ◽

Tairo Kimura ◽

...

Keyword(s):

Visual Field ◽

Visual Field Defect ◽

Open Angle Glaucoma ◽

Mean Deviation ◽

Open Angle ◽

Field Defect

Download Full-text

Location of visual field defect and optic disc assessment by confocal scanning laser ophthalmoscope in early normal tension glaucoma

Acta Ophthalmologica ◽

10.1111/j.1755-3768.2011.2253.x ◽

2011 ◽

Vol 89 (s248) ◽

pp. 0-0

Author(s):

KI JUNG ◽

CK PARK

Keyword(s):

Visual Field ◽

Optic Disc ◽

Visual Field Defect ◽

Normal Tension Glaucoma ◽

Scanning Laser Ophthalmoscope ◽

Scanning Laser ◽

Confocal Scanning Laser Ophthalmoscope ◽

Confocal Scanning ◽

Confocal Scanning Laser ◽

Field Defect

Download Full-text

Bilateral optic disc drusen with severe progressive visual field defect

Neuro-Ophthalmology ◽

10.1076/noph.25.4.229.8062 ◽

2001 ◽

Vol 25 (4) ◽

pp. 229-232

Author(s):

Tomoaki Usui ◽

Mineo Takagi ◽

Shigeru Hasegawa ◽

Haruki Abe ◽

Katsuhiko Nanba ◽

...

Keyword(s):

Visual Field ◽

Optic Disc ◽

Visual Field Defect ◽

Optic Disc Drusen ◽

Field Defect

Download Full-text

Nonarteritic Anterior Ischemic Optic Neuropathy following COVID-19 Vaccination: Consequence or Coincidence

Case Reports in Ophthalmological Medicine ◽

10.1155/2021/5126254 ◽

2021 ◽

Vol 2021 ◽

pp. 1-4

Author(s):

Rika Tsukii ◽

Yuka Kasuya ◽

Shinji Makino

Keyword(s):

Visual Acuity ◽

Visual Field ◽

Optic Disc ◽

Optic Neuropathy ◽

Visual Field Defect ◽

Anterior Ischemic Optic Neuropathy ◽

Ischemic Optic Neuropathy ◽

Optic Disc Swelling ◽

The Right ◽

Field Defect

To report a patient with nonarteritic anterior ischemic optic neuropathy (NA-AION) occurring soon after the COVID-19 vaccination. A 55-year-old woman presented with a 4-day history of inferior visual field disturbance in the right eye 7 days after receiving the first dose of Pfizer-BioNTech COVID-19 vaccine. Examination revealed a best-corrected visual acuity of 20/20 in both eyes. A relative afferent pupillary defect was observed in the right eye. Fundoscopy revealed diffuse optic disc swelling in the right eye, which was prominent above the optic disc. Goldmann visual field testing identified an inferior altitudinal visual field defect with I/2 isopter in the right eye. Although typical complete inferior visual field defect was not detected, a diagnosis of NA-AION was made. The patient was followed without any treatment. During the 2-month follow-up period, the optic disc swelling was gradually improved, and visual acuity was maintained 20/20; however, the optic disc looked diffusely pale in the right eye. Although it is uncertain whether the development of NA-AION after COVID-19 vaccination was consequential or coincidental, we speculate that the close temporal relationship with COVID-19 vaccination suggests the possibility of vasculopathy on the microvascular network of optic nerve head as background of inflammatory or immune-mediated element to the timing of the onset of NA-AION. The aim of this case report is to present this biological plausibility and to elucidate potential ophthalmological complications.

Download Full-text

Conservative Management of Pituitary Macroadenoma Contacting the Optic Apparatus

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques ◽

10.1017/s0317167100051532 ◽

2010 ◽

Vol 37 (6) ◽

pp. 837-842 ◽

Cited By ~ 10

Author(s):

Won Hyung A. Ryu ◽

Samantha Tam ◽

Brian Rotenberg ◽

Mohamed Ahmed Labib ◽

Donald Lee ◽

...

Keyword(s):

Visual Field ◽

Visual Function ◽

Visual Field Defect ◽

Tertiary Care ◽

Case Series ◽

Pituitary Macroadenoma ◽

Retrospective Case ◽

Imaging Characteristics ◽

Field Defect

AbstractObjectives:To describe the tumor characteristics and visual function in conservatively managed patients with non-functioning pituitary macroadenoma (NFMA) that contacted/compressed the visual pathway.Design:Retrospective case-series.Setting:Tertiary-care academic institution.Participants:Six patients with diagnosis of NFMA.Main Outcome:Visual function and radiological characteristics of the optic apparatus and pituitary tumor.Results:All patients had radiological evidence of optic apparatus compression but only one had visual field defect at the initial presentation. While two of the six patients developed visual field changes during follow-up (41±34.8 months), the patient with visual field defect at the time of diagnosis improved to normal vision.Conclusions:Select NFMAs that contact the optic apparatus, without visual dysfunction, may be managed with close ophthalmological and radiographic monitoring, depending on tumor and imaging characteristics. This may be of particular relevance in patients considered to have a high peri-operative risk, such as advanced age or significant co-morbidities.

Download Full-text

Navigated perilesional transcranial magnetic stimulation can improve post-stroke visual field defect: A double-blind sham-controlled study

Restorative Neurology and Neuroscience ◽

10.3233/rnn-211181 ◽

2021 ◽

pp. 1-9

Author(s):

Nevine El Nahas ◽

Ahmed M. Elbokl ◽

Eman Hamid Abd Eldayem ◽

Tamer M. Roushdy ◽

Randa M. Amin ◽

...

Keyword(s):

Transcranial Magnetic Stimulation ◽

Visual Field ◽

Visual Field Defect ◽

Magnetic Stimulation ◽

Controlled Study ◽

Mean Deviation ◽

Automated Perimetry ◽

Post Stroke ◽

Residual Vision ◽

Field Defect

Background: Visual field defects (VFD) usually do not show improvement beyond 12 weeks from their onset. It has been shown that repetitive presentation of a stimulus to areas of residual vision in cases of visual field defect can improve vision. The counterpart of these areas in the brain are the partially damaged brain regions at the perilesional areas where plasticity can be enhanced. Objective: We aimed to study the effect of navigated repetitive transcranial magnetic stimulation (rTMS) applied to perilesional areas on the recovery of patients with cortical VFD. Methods: Thirty-two patients with cortical VFD secondary to stroke of more than 3 months duration received 16 sessions of either active or sham high frequency navigated perilesional rTMS. Automated perimetry and visual functioning questionnaire (VFQ-25) were performed at baseline and after completion of the sessions. Results: The active group showed significant improvement after intervention, compared to the sham group, in both mean deviation (MD), visual field index (VFI) and in the VFQ-25 scores. Conclusions: Navigated rTMS is a new treatment option for post-stroke VFD as it can selectively stimulate areas of residual vision around the infarcted tissue, improving the threshold of visual stimulus detection which could be used alone or in combination with existing therapies.

Download Full-text