Accuracy of frozen section diagnosis in ovarian tumors: Is there a change in the course of time?

2003 ◽  
Vol 13 (5) ◽  
pp. 593-597 ◽  
Author(s):  
M. Gol ◽  
A. Baloglu ◽  
S. Yigit ◽  
M. Dogan ◽  
Ç. Aydin ◽  
...  
Keyword(s):  
Frozen Section ◽  
Correct Diagnosis ◽  
False Negative ◽  
Ovarian Tumors ◽  
Borderline Ovarian Tumors ◽  
Frozen Section Examination ◽  
Benign Ovarian Tumor ◽  
Frozen Section Diagnosis ◽  
Accuracy Rates ◽  
Higher Sensitivity

A retrospective study of 222 ovarian biopsy results between January 1, 2000 and August 31, 2002 was examined to determine the accuracy of frozen section diagnosis. In addition we reviewed all previous studies that examined the accuracy rates of frozen section diagnosis in ovarian tumors. Histopathologic examination results of frozen section biopsies were concordant with paraffin diagnosis in 92% of all cases. The sensitivity rates for benign, malignant, and borderline ovarian tumors were 98%, 88.7%, and 61%, respectively. There were five (2.2%) false-positive (overdiagnosed), and 13 (5.4%) false-negative (underdiagnosed) patients in frozen section examination. Frozen section examination of mucinous tumors showed higher underdiagnosis rates (20%). Review of previous studies showed no significant variation in accuracy rates of frozen section diagnosis for benign and malignant ovarian tumors, in relation with time. We found low accuracy rates for borderline ovarian tumors which was similar with the previous studies. Hovewer, there were consistent and relatively higher sensitivity rates for borderline ovarian tumors in the recent studies. As a result, we conclude that frozen section evaluation in identifying a malignant or benign ovarian tumor is accurate enough for the correct diagnosis. Since accuracy rates for borderline ovarian tumors are low, we should have more improvement in the correct diagnosis.

scholarly journals Accuracy of Intraoperative Frozen Section Diagnosis of Borderline Ovarian Tumors by Hospital Type

2019 ◽  
Vol 26 (1) ◽  
pp. 87-93 ◽  
Author(s):  
Jaimin S. Shah ◽  
Michael Mackelvie ◽  
David M. Gershenson ◽  
Preetha Ramalingam ◽  
Marylee M. Kott ◽  
...  
Keyword(s):  
Frozen Section ◽  
Ovarian Tumors ◽  
Hospital Type ◽  
Intraoperative Frozen Section ◽  
Borderline Ovarian Tumors ◽  
Frozen Section Diagnosis

Does Intraoperative Frozen Section Diagnosis Correlate with Final Pathology in Borderline Ovarian Tumors

2017 ◽  
Vol 147 (1) ◽  
pp. 217-218
Author(s):  
J. Shah ◽  
M. Mackelvie ◽  
P. Ramalingam ◽  
P. Gauthier ◽  
M. Kott ◽  
...  
Keyword(s):  
Frozen Section ◽  
Ovarian Tumors ◽  
Final Pathology ◽  
Intraoperative Frozen Section ◽  
Borderline Ovarian Tumors ◽  
Frozen Section Diagnosis

Accuracy of frozen section diagnosis of borderline ovarian tumors

2011 ◽  
Vol 122 (1) ◽  
pp. 127-131 ◽  
Author(s):  
Taejong Song ◽  
Chel Hun Choi ◽  
Ha-Jeong Kim ◽  
Min Kyu Kim ◽  
Tae-Joong Kim ◽  
...  
Keyword(s):  
Frozen Section ◽  
Ovarian Tumors ◽  
Borderline Ovarian Tumors ◽  
Frozen Section Diagnosis

scholarly journals The value of frozen section evaluation in the management of borderline ovarian tumors

2011 ◽  
Vol 7 (4) ◽  
pp. 416 ◽  
Author(s):  
Emre Gultekin ◽  
Basak Cingillioglu ◽  
Muzaffer Sanci ◽  
OzgeElmastas Gultekin ◽  
Sevil Sayhan ◽  
...  
Keyword(s):  
Frozen Section ◽  
Ovarian Tumors ◽  
Borderline Ovarian Tumors ◽  
Section Evaluation

Frozen section in borderline ovarian tumors: is it reliable?

2014 ◽  
Vol 181 ◽  
pp. 115-118 ◽  
Author(s):  
Isin Ureyen ◽  
Taner Turan ◽  
Derya Akdag Cirik ◽  
Tolga Tasci ◽  
Nurettin Boran ◽  
...  
Keyword(s):  
Frozen Section ◽  
Ovarian Tumors ◽  
Borderline Ovarian Tumors

scholarly journals OP03.07: Borderline ovarian tumors and frozen section: role of preoperative He4 and ROMA score to increase frozen section accuracy

2015 ◽  
Vol 46 ◽  
pp. 61-61
Author(s):  
S. Gizzo ◽  
M. Noventa ◽  
A. Vitagliano ◽  
M. Quaranta ◽  
R. Venturella ◽  
...  
Keyword(s):  
Frozen Section ◽  
Ovarian Tumors ◽  
Borderline Ovarian Tumors

scholarly journals Reliability of Telepathology for Frozen Section Service

2000 ◽  
Vol 21 (3-4) ◽  
pp. 213-222 ◽  
Author(s):  
Uwe Wellnitz ◽  
Bernd Binder ◽  
Peter Fritz ◽  
Godehard Friedel ◽  
Peter Schwarzmann
Keyword(s):  
Diagnostic Accuracy ◽  
Technological Development ◽  
Frozen Section ◽  
False Negative ◽  
Daily Practice ◽  
Histopathological Diagnosis ◽  
Time Saving ◽  
Surgical Interventions ◽  
Average Accuracy ◽  
Frozen Section Diagnosis

One of the most promising applications of telepathology (pathology at a distance by electronic transmission of images in pathology) is frozen section diagnosis, especially because by means of this tool operations requiring an intraoperative histopathological diagnosis are feasible at hospitals without a pathologist on‐site. For the introduction of this diagnostic tool into pathologist's daily practice the evidence of its diagnostic accuracy comparable to that of the conventional frozen section diagnosis is crucial.For this purpose the literature on the diagnostic accuracy of telepathological frozen section diagnosis was reviewed. In a metaanalysis these studies and reports, in which a total of more than 1290 cases had been examined, showed a slightly lower overall diagnostic accuracy (of the telepathological frozen section diagnosis) of about 0.91 than the conventional frozen section diagnosis with an average accuracy of about 0.98 found in an analysis of several studies (on frozen section diagnosis of different organs). This difference is at least predominantly caused by a higher rate of deferred and false negative frozen section diagnoses in the telepathological method, while the specificity of both methods, each more than 0.99 was not significantly different.In conclusion, the introduction of a telepathological frozen section diagnosis for hospitals without an acceptable access to a pathologist is justifiable already at the current state of the technological development especially when considering the advantages (time saving, reduction in costs) compared to the alternative of surgical interventions without access to an intraoperative diagnosis.

Accuracy of Frozen Section Diagnosis of the Salivary Gland

1987 ◽  
Vol 96 (4) ◽  
pp. 325-330 ◽  
Author(s):  
Douglas R. Gnepp ◽  
Willa Rae Rader ◽  
Stewart F. Cramer ◽  
Linda L. Cook ◽  
James Sciubba
Keyword(s):  
Salivary Gland ◽  
Malignant Tumor ◽  
Benign Tumor ◽  
Malignant Tumors ◽  
Frozen Section ◽  
Frozen Sections ◽  
Acinic Cell ◽  
Frozen Section Examination ◽  
Permanent Section ◽  
Frozen Section Diagnosis

Three hundred and one salivary gland lesions (162 benign, 72 malignant, and 67 benign non-neoplastic) of 677 cases were evaluated by use of intraoperative frozen sections by 66 pathologists. In seven patients, the diagnosis was deferred for permanent sections. In four cases (1.3%), the diagnosis at permanent section changed from one category of benign tumor to another, and in five cases (1.7%), from one category of malignant tumor to another. In four tumors, a frozen section diagnosis of benign was changed to malignant on permanent sectioning; all four involved acinic cell carcinomas. Only two tumors were incorrectly diagnosed as malignant. We conclude that diagnoses of most salivary gland lesions based on frozen section examination are reliable and accurate. However, the literature does indicate that caution should be exercised when malignant tumors are dealt with.

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