Hydrazine derivatives. III. A study of alkylation of guanazole

1976 ◽  
Vol 54 (22) ◽  
pp. 3620-3625 ◽  
Author(s):  
José J. Fuentes ◽  
Jacques A. Lenoir
Keyword(s):  
Aqueous Media ◽  
Alkyl Halides ◽  
Hydrazine Derivatives ◽  
Derivatives Of

Spectroscopic results from mono- and dibenzylidene derivatives of 1-alkylguanazoles establish that alkylation of 3,5-diamino-1,2,4-triazole (guanazole) with alkyl halides in basic non-aqueous media occurs at position N-1.

ChemInform Abstract: Addition of Hydrazine to 4,7-Dihydro[1,2,4]triazolo[1,5-a]pyrimidines: Hydrazine Derivatives of 4,5,6,7-Tetrahydro[1,2,4]triazolo[1,5-a]pyrimidine.

ChemInform ◽  
2010 ◽  
Vol 41 (16) ◽  
Author(s):  
Sergey A. Komykhov ◽  
Konstantin S. Ostras ◽  
Kyryl M. Kobzar ◽  
Vladimir I. Musatov ◽  
Sergey M. Desenko
Keyword(s):  
Hydrazine Derivatives ◽  
Derivatives Of

ChemInform Abstract: Facile Synthesis of Hydrazine Derivatives of 5H-Pyrrolo[3,4-b]pyrazine and 1H-Pyrrolo[3,4-b]quinoxaline.

ChemInform ◽  
2014 ◽  
Vol 45 (23) ◽  
pp. no-no
Author(s):  
Olga V. Hordiyenko ◽  
Igor V. Rudenko ◽  
Irina A. Zamkova ◽  
Oleksandr V. Denisenko ◽  
Angelina V. Biitseva ◽  
...  
Keyword(s):  
Facile Synthesis ◽  
Hydrazine Derivatives ◽  
Derivatives Of

scholarly journals CHEMISTRY AND SYNTHESIS OF SOME DIHYDRO-2H-l,4-BENZOTHIAZINE DERIVATIVES

1966 ◽  
Vol 44 (11) ◽  
pp. 1247-1258 ◽  
Author(s):  
Raj Nandan Prasad ◽  
Karin Tietje
Keyword(s):  
Alkyl Halides ◽  
Reduction Product ◽  
Alkyl Derivatives ◽  
Reaction Proceeds ◽  
Thiazine Ring ◽  
Derivatives Of ◽  
Compound Xviii ◽  
Acyl Derivatives

The formation of 3-oxo-3,4-dihydro-2H-1,4-benzothiazine (IIIa) by cyclization of alkyl 2-haloacetamidophenyl sulfides (I) was investigated; it is proposed that the reaction proceeds via a six-membered sulfonium halide. The preparation of 4-alkyl derivatives of IIIa and of 4-alkyl and 4-acyl derivatives of its reduction product 3,4-dihydro-2H-1,4-benzothiazine (Va) is described. Acylation of Va was shown to proceed without opening of the thiazine ring. Preparation of the O-benzoyl, N-benzoyl, and O,N-dibenzoyl derivatives of 2-(β-hydroxyethyl-mercapto)aniline (VIII) has permitted clarification of the confusion in the literature with respect to the derivatives of Va and VIII. Compound XVIII, the 1,1-dioxide of IIIa, undergoes C-alkylation at the 2-position when treated with alkyl halides, rather than O-alkylation as previously suggested.

Facile Synthesis of Hydrazine Derivatives of 5H-Pyrrolo[3,4-b]pyrazine and 1H-Pyrrolo[3,4-b]quinoxaline

Synthesis ◽  
2013 ◽  
Vol 45 (24) ◽  
pp. 3375-3382 ◽  
Author(s):  
Olga Hordiyenko ◽  
Igor Rudenko ◽  
Irina Zamkova ◽  
Oleksandr Denisenko ◽  
Angelina Biitseva ◽  
...  
Keyword(s):  
Facile Synthesis ◽  
Hydrazine Derivatives ◽  
Derivatives Of

Notizen: The Synthesis of a New Fused Thiazolo [4,3-c] -1,2,4-triazole System and its Derivatives

1976 ◽  
Vol 31 (6) ◽  
pp. 853-856 ◽  
Author(s):  
Nazmi Abd Elatif Kassab ◽  
Sanaa Osman Abd Allah ◽  
Hamed Abdel Reheem Ead
Keyword(s):  
Potassium Salt ◽  
Aromatic Aldehydes ◽  
Alkyl Halides ◽  
Formaldehyde Solution ◽  
Derivatives Of

Cyclisation of the 4-phenylhydrazono derivatives of 2-thiazolidinone or 2-thiazolidinethione (1) with formaldehyde solution or with aromatic aldehydes yields 2-phenyl-2,3-dihydrothiazolo[4,3-c]-1,2,4-triazol-5-one or its 5-thiocarbonyl analogue (2). Condensing 2 with aromatic aldehydes afforded the corresponding 7-arylidene derivatives (8).The 5-arylidene derivatives of 4-anisylimino-2-thiazolidinethione (5) were obtained by condensing 4 with aromatic aldehydes. The potassium salt of 5 reacts readily with alkyl halides to yield the 5-arylidene derivatives of 4-anisylimino-2-alkylmercapto-2-thiazoline (6).

Synthesis and study of the cytotoxic properties of bis-(2-fluoroethyl)-amino- and N,N-bis-(2-chloroethyl)-hydrazine derivatives of furan

1968 ◽  
Vol 2 (2) ◽  
pp. 65-69
Author(s):  
R. Yu. Kalnberg ◽  
K. K. Venter ◽  
N. M. Sukhova ◽  
A. A. Zidermane ◽  
A. Zh. Dauvarte ◽  
...  
Keyword(s):  
Hydrazine Derivatives ◽  
Derivatives Of
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