Redox regulation of stem cell mobilizationThis article is one of a selection of papers published in a special issue on Advances in Cardiovascular Research.
2009 ◽
Vol 87
(12)
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pp. 989-995
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Keyword(s):
A growing body of evidence supports the role of redox signaling in the mechanisms of hematopoietic stem cell mobilization and homing. Cytokines and adhesion molecules control stem cell mobilization through a redox-regulated process. The FoxO–SirT network appears to be intimately involved in redox-regulated stem cell homeostasis, whereas the process of stem cell differentiation is regulated by redox effector factor-1 (Ref-1) protein. Lack of oxygen (hypoxia), specifically controlled hypoxia, can stimulate the growth of the stem cells in their niche, and hypoxia-inducible factor (HIF)-1α appears to play a significant role in their maintenance and homing mechanism.
2017 ◽
Vol 56
(3)
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pp. 470-473
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2017 ◽
Vol 56
(6)
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pp. 795-799
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2009 ◽
Vol 9
(8)
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pp. 1099-1106
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2013 ◽
Vol 19
(9)
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pp. 1301-1309
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2017 ◽
Vol 36
(4)
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pp. 399-409
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