IMAGE-GUIDED SURGICAL PROCEDURES AND INTERVENTIONS: CHALLENGES AND OPPORTUNITIES

Author(s):  
Terry Peters
EBioMedicine ◽  
2021 ◽  
Vol 70 ◽  
pp. 103514
Author(s):  
Giulia Sprugnoli ◽  
Simone Rossi ◽  
Alexander Rotenberg ◽  
Alvaro Pascual-Leone ◽  
Georges El-Fakhri ◽  
...  

2003 ◽  
Vol 8 (2) ◽  
pp. 98-106 ◽  
Author(s):  
P. Jannin ◽  
M. Raimbault ◽  
X. Morandi ◽  
L. Riffaud ◽  
B. Gibaud

2021 ◽  
Author(s):  
Connor W. Barth ◽  
Lei G. Wang ◽  
Antonio Montano ◽  
Alexander L. Antaris ◽  
Alwin Klaassen ◽  
...  

Author(s):  
Daivik B. Vyas ◽  
Lily H. Kim ◽  
Allen Ho ◽  
Eric S. Sussman ◽  
Arjun V. Pendharkar ◽  
...  

Trigeminal neuralgia is a debilitating neuropathic condition characterized by recurrent paroxysms of shock-like pain across the distribution of the trigeminal nerve, often brought on by innocuous stimuli. Available therapies presently include symptomatic management using anti-convulsant drugs and invasive surgical procedures to target the pathogenic drivers of disease or ablate the trigeminal nerve. Radiosurgery is a treatment modality that offers a minimally invasive, low-risk alternative that has promising clinical utility in the management of refractory trigeminal neuralgia. Radiosurgical approaches like Gamma Knife (GKS) and Cyberknife (CK) utilize image-guided, algorithm-defined dose contouring to disrupt pathogenic pain signaling by delivering targeted amounts of radiation along different points on the trigeminal nerve. This chapter reviews the structure of radiotherapy paradigms, treatment protocol, major outcomes, associated risks, relative clinical utility, and areas of further research that underlie the use of CK and GKS in managing trigeminal neuralgia.


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