Formal semantics of an algorithm for translating model-based specifications to concurrent constraint programs

Author(s):  
Tim Wahls ◽  
Gary T. Leavens
Keyword(s):  
2015 ◽  
Vol 27 (3) ◽  
pp. 332-375 ◽  
Author(s):  
MAX KANOVICH ◽  
TAJANA BAN KIRIGIN ◽  
VIVEK NIGAM ◽  
ANDRE SCEDROV ◽  
CAROLYN TALCOTT ◽  
...  

Activities such as clinical investigations (CIs) or financial processes are subject to regulations to ensure quality of results and avoid negative consequences. Regulations may be imposed by multiple governmental agencies as well as by institutional policies and protocols. Due to the complexity of both regulations and activities, there is great potential for violation due to human error, misunderstanding, or even intent. Executable formal models of regulations, protocols and activities can form the foundation for automated assistants to aid planning, monitoring and compliance checking. We propose a model based on multiset rewriting where time is discrete and is specified by timestamps attached to facts. Actions, as well as initial, goal and critical states may be constrained by means of relative time constraints. Moreover, actions may have non-deterministic effects, i.e. they may have different outcomes whenever applied. We present a formal semantics of our model based on focused proofs of linear logic with definitions. We also determine the computational complexity of various planning problems. Plan compliance problem, for example, is the problem of finding a plan that leads from an initial state to a desired goal state without reaching any undesired critical state. We consider all actions to be balanced, i.e. their pre- and post-conditions have the same number of facts. Under this assumption on actions, we show that the plan compliance problem is PSPACE-complete when all actions have only deterministic effects and is EXPTIME-complete when actions may have non-deterministic effects. Finally, we show that the restrictions on the form of actions and time constraints taken in the specification of our model are necessary for decidability of the planning problems.


1985 ◽  
Vol 14 (198) ◽  
Author(s):  
Kurt Jensen ◽  
Erik Meineche Schmidt

This paper describes the formal semantics of a subset of PASCAL by means of a semantic model based on a combination of denotational semantics and high-level Petri nets. It is our intention that the paper be used as part of the written material for an introductory course in Computer Science.


2020 ◽  
Vol 43 ◽  
Author(s):  
Peter Dayan

Abstract Bayesian decision theory provides a simple formal elucidation of some of the ways that representation and representational abstraction are involved with, and exploit, both prediction and its rather distant cousin, predictive coding. Both model-free and model-based methods are involved.


2001 ◽  
Vol 7 (S2) ◽  
pp. 578-579
Author(s):  
David W. Knowles ◽  
Sophie A. Lelièvre ◽  
Carlos Ortiz de Solόrzano ◽  
Stephen J. Lockett ◽  
Mina J. Bissell ◽  
...  

The extracellular matrix (ECM) plays a critical role in directing cell behaviour and morphogenesis by regulating gene expression and nuclear organization. Using non-malignant (S1) human mammary epithelial cells (HMECs), it was previously shown that ECM-induced morphogenesis is accompanied by the redistribution of nuclear mitotic apparatus (NuMA) protein from a diffuse pattern in proliferating cells, to a multi-focal pattern as HMECs growth arrested and completed morphogenesis . A process taking 10 to 14 days.To further investigate the link between NuMA distribution and the growth stage of HMECs, we have investigated the distribution of NuMA in non-malignant S1 cells and their malignant, T4, counter-part using a novel model-based image analysis technique. This technique, based on a multi-scale Gaussian blur analysis (Figure 1), quantifies the size of punctate features in an image. Cells were cultured in the presence and absence of a reconstituted basement membrane (rBM) and imaged in 3D using confocal microscopy, for fluorescently labeled monoclonal antibodies to NuMA (fαNuMA) and fluorescently labeled total DNA.


Author(s):  
Charles Bouveyron ◽  
Gilles Celeux ◽  
T. Brendan Murphy ◽  
Adrian E. Raftery

Author(s):  
Jonathan Jacky ◽  
Margus Veanes ◽  
Colin Campbell ◽  
Wolfram Schulte
Keyword(s):  

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