Oxygen consumption in frog sartorius muscle: variation following an applied stretch

1966 ◽  
Vol 211 (2) ◽  
pp. 525-528 ◽  
Author(s):  
RJ Baskin ◽  
VN Galluzzi
Keyword(s):  
Oxygen Consumption ◽  
Sartorius Muscle ◽  
Frog Sartorius Muscle ◽  
Frog Sartorius

scholarly journals Kinetics of oxygen consumption after a single isometric tetanus of frog sartorius muscle at 20 degrees C.

1978 ◽  
Vol 71 (5) ◽  
pp. 559-580 ◽  
Author(s):  
M Mahler
Keyword(s):  
Oxygen Consumption ◽  
Time Course ◽  
Atp Hydrolysis ◽  
Preceding Paper ◽  
Nonlinear Process ◽  
Forthcoming Paper ◽  
Sartorius Muscle ◽  
Frog Sartorius Muscle ◽  
Kinetics Of ◽  
Frog Sartorius

The time-course of the rate of oxygen consumption (QO2) has been measured in the excised frog sartorius muscle after single isometric tetani of 0.1-1.0 s at 20 degrees C. To measure deltaQO2(t), the change in QO2 from its basal level, a novel method was devised, based on the validity in this tissue of the one-dimensional diffusion equation for oxygen, established in the preceding paper. After a tetanus, deltaQO2 reached a peak within 45-90 s, then declined exponentially, and could be well fit by deltaQO2(t) = QO + Q1(epsilon -k1t - epsilon-k2t). tau2 (= 1/k2), which characterized the rise of deltaQO2, was a decreasing function of tetanus duration (range: from 1.1 +/- 0.28 min [nu = 5] for a 0.1-s tetanus, to 0.34 +/- 0.05 min [nu = 8] for a 1.0-sec tetanus). tau1 (= 1/k1), which characterized the decline of deltaQO2, was not dependent on tetanus duration, with mean 3.68 +/- -.24 min (nu = 46). A forthcoming paper in this series shows that these kinetics of deltaQO2 are the responses to impulse-like changes in the rate of ATP hydrolysis. The variation of tau2 with tetanus duration thus indicates the involvement of a nonlinear process in the coupling of O2 consumption to ATP hydrolysis. However, the monoexponential decline of deltaQO2(t), with time constant independent of tetanus duration, suggests that during this phase, the coupling is rate-limited by a single reaction with apparent first order kinetics.

Effect of stretch on O2 consumption of resting and active frog sartorius muscle

1962 ◽  
Vol 203 (4) ◽  
pp. 731-734 ◽  
Author(s):  
W. J. Whalen ◽  
L. C. Collins ◽  
H. Berry
Keyword(s):  
Oxygen Consumption ◽  
Heart Muscle ◽  
Heat Liberation ◽  
Sartorius Muscle ◽  
O2 Consumption ◽  
Frog Sartorius Muscle ◽  
Resting Tension ◽  
Resting Muscle ◽  
Frog Sartorius

Oxygen consumption and resting and developed tension were measured simultaneously while the length of the muscle was increased by known increments. The Qo2 of resting muscle increased about 1% for each 1% extension beyond the relaxed length. Both resting tension and length were directly related to Qo2. In a stimulated muscle, Qo2 and frequency of contraction showed a highly significant correlation. The Qo2 of a stimulated muscle increased as the length and total tension (developed plus resting) increased. Neither Qo2 nor the increment in Qo2 above the resting level correlated significantly with developed tension. These latter findings differ from the results predicted from heat-liberation experiments. The results found here are not markedly different from those we found in heart muscle.

Constancy of Axial Spacings in Frog Sartorius Muscle during Contraction

Nature ◽  
1965 ◽  
Vol 206 (4991) ◽  
pp. 1358-1358 ◽  
Author(s):  
H. E. HUXLEY ◽  
W. BROWN ◽  
K. C. HOLMES
Keyword(s):  
Sartorius Muscle ◽  
Frog Sartorius Muscle ◽  
Frog Sartorius
Sign in / Sign up

Export Citation Format

Share Document