Contrast gain control occurs independently of both parvalbumin-positive interneuron activity and shunting inhibition in auditory cortex
2020 ◽
Vol 123
(4)
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pp. 1536-1551
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Keyword(s):
We investigated whether contrast gain control is mediated by shunting inhibition from parvalbumin-positive interneurons in auditory cortex. We performed extracellular and intracellular recordings in mouse auditory cortex while presenting sensory stimuli with varying contrasts and manipulated parvalbumin-positive interneuron activity using optogenetics. We show that while parvalbumin-positive interneuron activity modulates the gain of cortical responses, this activity is not the primary mechanism for contrast gain control in auditory cortex.
2018 ◽
Vol 120
(4)
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pp. 1872-1884
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Keyword(s):
2008 ◽
Vol 26
(2)
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pp. 219-249
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Keyword(s):
Keyword(s):
2007 ◽
Vol 27
(10)
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pp. 2636-2645
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2002 ◽
Vol 13
(6)
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pp. 1497-1503
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