scholarly journals A Malignant Granular Cell Tumor Excised with Mohs Micrographic Surgery

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
David Crowe ◽  
Elias E. Ayli ◽  
Hugh M. Gloster
Keyword(s):  
Metastatic Disease ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Mohs Micrographic Surgery ◽  
Micrographic Surgery ◽  
Diagnostic Challenge ◽  
Early Presentation ◽  
Malignant Granular Cell Tumor

Malignant granular cell tumors are extremely rare, aggressive neoplasms displaying rapid growth and frequent associated metastatic disease. Excision and evaluation for metastatic disease are mandatory. We present a 54-year-old patient with a malignant granular cell tumor, treated with Mohs micrographic surgery. Cutaneous granular cell tumors are uncommon neoplasms, likely of perineural origin. Most follow a benign and uneventful course, with wide local excision being the treatment of choice (Enzinger, 1988). The malignant granular cell tumor is an extremely rare, aggressive variant, which provides a diagnostic challenge and management dilemma, especially with early presentation when it may be mistaken for other entities. There is also controversy regarding surgical management and follow-up of both benign and malignant granular cell tumors.

Mohs Micrographic Surgery for Granular Cell Tumor Using S-100 Immunostain

2002 ◽  
Vol 28 (11) ◽  
pp. 1076-1078
Author(s):  
SIDNEY B. SMITH ◽  
MARY F. FARLEY ◽  
JOHN G. ALBERTINI ◽  
DIRK M. ELSTON
Keyword(s):  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Mohs Micrographic Surgery ◽  
Micrographic Surgery ◽  
S 100

Mohs Micrographic Surgery for Granular Cell Tumor Using S-100 Immunostain

2002 ◽  
Vol 28 (11) ◽  
pp. 1076-1078 ◽  
Author(s):  
Sidney B. Smith ◽  
Mary F. Farley ◽  
John G. Albertini ◽  
Dirk M. Elston
Keyword(s):  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Mohs Micrographic Surgery ◽  
Micrographic Surgery ◽  
S 100

scholarly journals Multifocal Pulmonary Granular Cell Tumor Presenting with Postobstructive Pneumonia

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Samid M. Farooqui ◽  
Muhammad S. Khan ◽  
Laura Adhikari ◽  
Viral Doshi
Keyword(s):  
Granular Cell Tumor ◽  
Main Bronchus ◽  
Granular Cell ◽  
Middle Lobe ◽  
Cell Tumor ◽  
Diagnostic Challenge ◽  
Right Middle Lobe ◽  
The Right ◽  
Lost To Follow Up

Granular cell tumor (GCT) is a neoplasm of Schwann cell origin. Its presence in the aerodigestive tract is uncommon and becomes a diagnostic challenge on initial presentation. Our case is of a 59-year-old woman who presented to the emergency department with a history of productive cough and dyspnea associated with fever and chest pain. An initial chest X-ray (CXR) showed a right middle lobe consolidation with follow-up Computed Tomography (CT) scan showing a mass in the right bronchus. Bronchoscopy revealed a polypoid, sessile granular mass in the right bronchus intermedius with multiple white lesions in trachea, left main bronchus, and right upper bronchi. Histology revealed a benign GCT. Bronchoalveolar lavage from the right middle lobe grew Streptococcus pneumoniae. Patient was treated with intravenous levofloxacin during hospital stay and discharged on a 7-day course of oral antibiotics to be followed as outpatient but was lost to follow-up. GCT can present as a polypoid tumor causing recurrent postobstructive pneumonia. Surgical resection is the most successful treatment option. The tumor is more common in third and fourth decade of life and our patient is the oldest patient, according to our knowledge, to have a GCT.

scholarly journals Malignant granular cell tumor of the arm – case report

2021 ◽  
Vol 4 (1) ◽  
pp. 3-8
Author(s):  
Mihai Mehedinţu ◽  
Răzvan Danciu ◽  
Anca I. Toma ◽  
Corina Ştefan ◽  
Cristian R. Jecan
Keyword(s):  
Granular Cell Tumor ◽  
Clinical Presentation ◽  
Histopathological Examination ◽  
Granular Cell ◽  
Surgical Excision ◽  
Female Gender ◽  
Cell Tumor ◽  
Malignant Granular Cell Tumor ◽  
Tissue Cancer

Abstract Granular cell tumor (GCT) is a rare form of soft tissue cancer that is usually benign. Its malignant evolution is encountered in less than 2% of cases, having a more rapid and unfavorable evolution. Clinical presentation betraying malignant features could be increased tumor size, rapid growth, deep localization, and female gender. This paper presents the case of a 52-year-old patient with a hard, rapidly evolving tumor in the left arm. The diagnosis of granular cell tumor was made based on histopathological examination using the Fanburg and Smith criteria to differentiate the formation as malignant, but with certainty this was subsequently confirmed by the existence of a metastasis. Surgical excision was performed and the evolution was favorable. Evolution and treatment differ depending on the benign or malignant form, but surgical treatment with wide local excision is recommended. This may be followed by chemotherapy or radiotherapy, and follow-up of patients for the rest of their lives is mandatory.

Malignant granular cell tumor of the posterior orbit

Orbit ◽  
1990 ◽  
Vol 9 (3) ◽  
pp. 155-163 ◽  
Author(s):  
Deborah I. Friedman ◽  
Narsing A. Rao ◽  
Alfredo A. Sadun ◽  
Peter W. Nichols ◽  
Richard Leung
Keyword(s):  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Malignant Granular Cell Tumor
Sign in / Sign up

Export Citation Format

Share Document