scholarly journals Comparison between Intravitreal Triamcinolone with Grid Laser Photocoagulation versus Bevacizumab with Grid Laser Photocoagulation Combinations for Branch Retinal Vein Occlusion

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Abdullah Ozkaya ◽  
Ugur Celik ◽  
Zeynep Alkin ◽  
Miray Faiz Turan ◽  
Ahmet Taylan Yazici ◽  
...  

Purpose. To compare the efficacy of intravitreal triamcinolone (IVT) and intravitreal bevacizumab (IVB), both combined with grid laser photocoagulation (GLP) for macular edema (ME) secondary to branch retinal vein occlusion (BRVO). Methods. Retrospective, comparative study. The newly diagnosed patients with ME secondary to BRVO who were treated with IVT and GLP or IVB and GLP were included. The main outcome measures were changed in the best corrected visual acuity (BCVA) and central retinal thickness (CRT) from the baseline to month 24. Results. Ninety-nine eyes of 99 patients were included. The change in BCVA was not statistically different in any time points between the two groups (P>0.05, for all). The change in CRT was not statistically different in any time points between the two groups (P>0.05, for all). The mean number of injections at month 24 was 2.38±1.06 in the IVT+GLP group and 4.17±1.30 in the IVB+GLP group (P=0.0001). The need for cataract surgery (P=0.01) and secondary glaucoma (P=0.03) occurrence were more common in IVT group. Conclusion. Both treatment modalities were effective in the treatment of ME secondary to BRVO. The number of injections was significantly lower in the IVT group than in the IVB group; however cataract and secondary glaucoma were more frequent in the IVT+GLP group than in the IVB+GLP group.

2011 ◽  
Vol 21 (4) ◽  
pp. 434-439 ◽  
Author(s):  
Angel Salinas-Alamán ◽  
Javier Zarranz-Ventura ◽  
Jose M. Caire González-Jauregui ◽  
Luis M. Sádaba-Echarri ◽  
Jesús Barrio-Barrio ◽  
...  

2019 ◽  
Vol 30 (2) ◽  
pp. 370-375
Author(s):  
Seoung Hyun An ◽  
Woo Jin Jeong

Purpose: To investigate the effect of early-scatter laser photocoagulation on the formation of collateral vessels in branch retinal vein occlusion. Methods: The medical records of 40 cases (40 patients) of branch retinal vein occlusion with macular edema were retrospectively reviewed. Of them, 23 patients were treated with intravitreal bevacizumab injection and 17 patients underwent intravitreal bevacizumab injection with additional laser treatment. Early-scatter laser photocoagulation was applied for capillary non-perfusion areas, regardless of retinal neovascularization. Collateral vessel presence, recurrence rate of macular edema, and number of intravitreal bevacizumab injections were compared between the groups. Results: During the follow-up period, collateral vessel formation was noted in 10/23 eyes (43.5%) in the intravitreal bevacizumab injection group and 15/17 eyes (88.2%) in the laser combined treatment group ( p = 0.004). The recurrence rate of macular edema was lower in the laser combined treatment group (29.4%) than in the intravitreal bevacizumab injection group (65.2%); this difference was statistically significant ( p = 0.025). The average numbers of intravitreal bevacizumab injections were 3.57 ± 3.23 in the intravitreal bevacizumab group and 2.14 ± 2.26 in the laser combined treatment group ( p = 0.044). Conclusion: Early-scatter laser photocoagulation promotes collateral vessel formation; the presence of collateral vessels seemed to affect the course of macular edema in branch retinal vein occlusion. Combined early-scatter laser photocoagulation treatment after intravitreal bevacizumab injection lowered the recurrence rate of macular edema and number of intravitreal bevacizumab injections in the cases of branch retinal vein occlusion.


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