scholarly journals Exponential Stability Analysis for Genetic Regulatory Networks with Both Time-Varying and Continuous Distributed Delays

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Lizi Yin ◽  
Yungang Liu

The global exponential stability is investigated for genetic regulatory networks with time-varying delays and continuous distributed delays. By choosing an appropriate Lyapunov-Krasovskii functional, new conditions of delay-dependent stability are obtained in the form of linear matrix inequality (LMI). The lower bound of derivatives of time-varying delay is first taken into account in genetic networks stability analysis, and the main results with less conservatism are established by interactive convex combination method to estimate the upper bound of derivative function of the Lyapunov-Krasovskii functional. In addition, two numerical examples are provided to illustrate the effectiveness of the theoretical results.

2018 ◽  
Vol 23 (6) ◽  
pp. 803-829 ◽  
Author(s):  
Selvakumar Pandiselvi ◽  
Raja Ramachandran ◽  
Jinde Cao ◽  
Grienggrai Rajchakit ◽  
Aly R. Seadawy ◽  
...  

In this typescript, we concerned the problem of delay-dependent approach of impulsive genetic regulatory networks besides the distributed delays, parameter uncertainties and time-varying delays. An advanced Lyapunov–Krasovskii functional are defined, which is in triple integral form. Combining the Lyapunov–Krasovskii functional with convex combination method and free-weighting matrix approach the stability conditions are derived with the help of linear matrix inequalities (LMIs). Some available software collections are used to solve the conditions. Lastly, two numerical examples and their simulations are conferred to indicate the feasibility of the theoretical concepts.


2012 ◽  
Vol 90 (10) ◽  
pp. 939-953 ◽  
Author(s):  
K. Mathiyalagan ◽  
R. Sakthivel

This paper presents some novel results on robust stabilization and H∞ control design for a class of uncertain discrete-time stochastic genetic regulatory networks (GRNs) with time-varying delays. The GRNs under consideration are subject to stochastic noise, time-varying, and norm bounded parameter uncertainties. By constructing a new Lyapunov–Krasovskii functional that contains some novel triple summation terms, we propose a state feedback gene controller to guarantee that the considered GRN is mean-square asymptotically stable about its equilibrium point for all admissible uncertainties. The other issue is to design a H∞ feedback gene controller so that the GRN is robustly stable with a prescribed H∞ disturbance attenuation level for all admissible uncertainties and for all delays to satisfy both the lower bound and upper bound of the interval time-varying delay. The obtained conditions are derived in terms of linear matrix inequalities (LMIs), which can be easily verified via the LMI toolbox. Finally, the control scheme has been implemented in a gene network model to illustrate the applicability and usefulness of the obtained results.


2014 ◽  
Vol 2014 ◽  
pp. 1-15 ◽  
Author(s):  
Jun Li ◽  
Manfeng Hu ◽  
Jinde Cao ◽  
Yongqing Yang ◽  
Yinghua Jin

This paper is concerned with the stability problem for a class of uncertain impulsive stochastic genetic regulatory networks (UISGRNs) with time-varying delays both in the leakage term and in the regulator function. By constructing a suitable Lyapunov-Krasovskii functional which uses the information on the lower bound of the delay sufficiently, a delay-dependent stability criterion is derived for the proposed UISGRNs model by using the free-weighting matrices method and convex combination technique. The conditions obtained here are expressed in terms of LMIs whose feasibility can be checked easily by MATLAB LMI control toolbox. In addition, three numerical examples are given to justify the obtained stability results.


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