scholarly journals Indocyanine Green Near-Infrared Fluorescence Imaging-Guided Laparoscopic Heminephrectomy for Left Ureteral Cancer in Patient with Horseshoe Kidney

2019 ◽  
Vol 2019 ◽  
pp. 1-5 ◽  
Author(s):  
Takao Natsuyama ◽  
Yozo Mitsui ◽  
Masato Uetani ◽  
Shigeyuki Ohta ◽  
Shin-ichi Hisasue
Keyword(s):  
Indocyanine Green ◽  
Near Infrared ◽  
Imaging System ◽  
Left Kidney ◽  
Horseshoe Kidney ◽  
Near Infrared Fluorescence ◽  
Nirf Imaging ◽  
Novel Approach ◽  
The Right ◽  
Near Infrared Fluorescence Imaging

Laparoscopic surgery for patients with a horseshoe kidney is challenging because of the location, aberrant vasculature, and difficulty with division of the isthmus with adequate hemostasis. We herein report performance of a laparoscopic heminephrectomy for left ureteral cancer in a patient with a horseshoe kidney under guidance from near-infrared fluorescence (NIRF) imaging using indocyanine green (ICG). A 62-year-old male was referred to our hospital for treatment of left ureteral cancer associated with a horseshoe kidney. We performed a laparoscopic left nephroureterectomy and bladder resection in June 2017. During the operation, the NIRF imaging system was used to evaluate the border of the kidney parenchyma isthmus after ligation of the left kidney vasculature supply. Interestingly, the dominant region of the right kidney showed strong ICG fluorescence as compared to the left kidney region. With the assistance of ICG-based NIRF imaging, isthmus division was performed with monopolar scissors and adequate hemostasis was obtained by electrocautery coagulation. This is the first report of use of an ICG-based NIRF imaging system and this novel approach can help to demarcate the left moiety isthmus from right one with more certainty.

scholarly journals Near Infrared Fluorescence Imaging to Assess Breast Flap Perfusion and Prevention of Ischemia: Case Report

2019 ◽  
Vol 103 (9-10) ◽  
pp. 473-476
Author(s):  
Ju Yong Cheong ◽  
David Goltsman ◽  
Sanjay Warrier
Keyword(s):  
Fluorescence Imaging ◽  
Near Infrared ◽  
Imaging System ◽  
Skin Flap ◽  
Color Temperature ◽  
Near Infrared Fluorescence ◽  
Clinical Method ◽  
Nirf Imaging ◽  
Near Infrared Fluorescence Imaging ◽  
Flap Perfusion

Introduction: Breast skin flap ischemia and necrosis is a serious consequence of breast reconstruction with reported incidence of 10% to 15%. Current clinical method of assessing breast skin flap perfusion includes combination of skin color, temperature, dermal edge bleeding, and capillary refill. Given the high incidence of ischemia and the presence of certain cohort of patient with greater risk, there is a need for an objective method of assessing the skin flap perfusion. Near infrared fluorescence imaging using indocyanine green is a new technique of assessing skin flap perfusion. We present a first reported case where breast skin flap ischemia was objectively identified intraoperatively by NIRF imaging, and this ischemia was reversed through active intra- and postoperative measures, which was objectively again identified by NIRF imaging. Case presentation: A 36-year-old female patient underwent bilateral nipple sparing mastectomies with immediate reconstruction using tissue expanders. Clinical assessment of the breast skin flap was equivocal. NIRF imaging using SPY imaging system (Novadaq Technologies Inc, Toronto, ON, Canada) showed poor perfusion in the periareolar region. As a result, it was decided to completely deflate the expander, actively warm the skin flap and encourage cutaneous perfusion through use of topical glycerin trinitrate patch. A repeat NIRF imaging 48 hours showed 10-fold increase in perfusion in the skin flap. Conclusion: NIRF imaging is a useful tool in assessing breast skin perfusion and to predict potential ischemia, which can aid in surgeon's management of patient.

scholarly journals Near-Infrared Fluorescence Imaging of Carotid Plaques in an Atherosclerotic Murine Model

Biomolecules ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 1753
Author(s):  
Xiaotian Wu ◽  
Amy Daniel Ulumben ◽  
Steven Long ◽  
Wataru Katagiri ◽  
Moses Q. Wilks ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Near Infrared ◽  
Imaging Systems ◽  
Short Exposure ◽  
Near Infrared Fluorescence ◽  
Nirf Imaging ◽  
Fda Approval ◽  
Diseased Vessel ◽  
The Right ◽  
Near Infrared Fluorescence Imaging

Successful imaging of atherosclerosis, one of the leading global causes of death, is crucial for diagnosis and intervention. Near-infrared fluorescence (NIRF) imaging has been widely adopted along with multimodal/hybrid imaging systems for plaque detection. We evaluate two macrophage-targeting fluorescent tracers for NIRF imaging (TLR4-ZW800-1C and Feraheme-Alexa Fluor 750) in an atherosclerotic murine cohort, where the left carotid artery (LCA) is ligated to cause stenosis, and the right carotid artery (RCA) is used as a control. Imaging performed on dissected tissues revealed that both tracers had high uptake in the diseased vessel compared to the control, which was readily visible even at short exposure times. In addition, ZW800-1C’s renal clearance ability and Feraheme’s FDA approval puts these two tracers in line with other NIRF tracers such as ICG. Continued investigation with these tracers using intravascular NIRF imaging and larger animal models is warranted for clinical translation.

scholarly journals Intra-operative assessment of the vascularisation of a cross section of the meniscus using near-infrared fluorescence imaging

2021 ◽  
Author(s):  
Peter van Schie ◽  
Thies J. N. van der Lelij ◽  
Maxime Gerritsen ◽  
Ruben P. J. Meijer ◽  
Ewoud R. A. van Arkel ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Cross Section ◽  
Near Infrared ◽  
Level Of Evidence ◽  
Camera System ◽  
Near Infrared Fluorescence ◽  
Nirf Imaging ◽  
Total Knee ◽  
Operative Assessment ◽  
Near Infrared Fluorescence Imaging

Abstract Purpose The purpose of this study was to assess whether the vascularisation of the meniscus could be visualised intra-operatively using near-infrared fluorescence (NIRF) imaging with indocyanine green (ICG) in patients undergoing total knee arthroplasty (TKA). Methods The anterior horn (i.e., Cooper classification: zones C and D) of the meniscus that was least affected (i.e., least degenerative) was removed during TKA surgery in ten patients to obtain a cross section of the inside of the meniscus. Thereafter, 10 mg of ICG was injected intravenously, and vascularisation of the cross section of the meniscus was assessed using the Quest spectrum NIRF camera system. We calculated the percentage of patients in whom vascularisation was observed intra-operatively using NIRF imaging compared to immunohistochemistry. Results Meniscal vascularisation using NIRF imaging was observed in six out of eight (75%) patients in whom vascularisation was demonstrated with immunohistochemistry. The median extent of vascularisation was 13% (interquartile range (IQR) 3–28%) using NIRF imaging and 15% (IQR 11–23%) using immunohistochemistry. Conclusion This study shows the potential of NIRF imaging to visualise vascularisation of the meniscus, as vascularisation was observed in six out of eight patients with histologically proven meniscal vascularisation. Level of evidence IV.

Application of Indocyanine Green Near-Infrared Fluorescence Imaging in Laparoscopic Colectomy for Metachronous Colon Cancer

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Hidekazu Takahashi ◽  
Takayuki Ogino ◽  
Norikatsu Miyoshi ◽  
Mamoru Uemura ◽  
Hirofumi Yamamoto ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Indocyanine Green ◽  
Fluorescence Imaging ◽  
Laparoscopic Colectomy ◽  
Near Infrared ◽  
Near Infrared Fluorescence ◽  
Near Infrared Fluorescence Imaging

scholarly journals Tissue-like phantoms for near-infrared fluorescence imaging system assessment and the training of surgeons

2006 ◽  
Vol 11 (1) ◽  
pp. 014007 ◽  
Author(s):  
Alec M. De Grand ◽  
Stephen J. Lomnes ◽  
Deborah S. Lee ◽  
Matthew Pietrzykowski ◽  
Shunsuke Ohnishi ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Near Infrared ◽  
Imaging System ◽  
Near Infrared Fluorescence ◽  
Fluorescence Imaging System ◽  
Training Of Surgeons ◽  
System Assessment ◽  
Near Infrared Fluorescence Imaging
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