scholarly journals Basal Cell Carcinoma Pathology Requests and Reports Are Lacking Important Information

2019 ◽  
Vol 2019 ◽  
pp. 1-5 ◽  
Author(s):  
Firas Al-Qarqaz ◽  
Khaldon Bodoor ◽  
Awad Al-Tarawneh ◽  
Haytham Eloqayli ◽  
Wisam Al Gargaz ◽  
...  

Introduction.Basal cell carcinoma (BCC) is the most common cancer affecting humans. Luckily it has negligible risk for metastasis; however it can be locally destructive to surrounding tissue. The diagnosis of this tumor relies on clinical and dermoscopic features; however confirmation requires biopsy and histologic examination. Based on clinical and pathologic findings, BCC is classified as low or high risk subtype. The clinician requesting pathology examination for BCC should provide the pathologist with detailed information including patient details, relevant clinical and medical history, site and type of the biopsy, and whether this is a primary or recurrent lesion. The pathologist on the other hand should write an adequate report containing a minimum of core set of parameters including type of BCC, depth of invasion, presence of lymphovascular or perineural invasion, and the excision margins.Objectives.The objective of this study is to evaluate whether requests by clinicians and pathology reports of BCC are adequate.Methods.This is a retrospective analysis done at the dermatology department, faculty of medicine at Jordan University of Science and Technology, Irbid, Jordan. Reports for the period from January 2003 to December 2017 were retrieved and analyzed for data completeness.Results.Most clinical request forms of BCC provided by clinicians are inadequate and lack important relevant information especially in regard to lesion history, patient medical history, and whether BCC is a primary or a recurrent one. Pathology reports for BCC cases also have significant deficiency especially in describing the histologic subtype, depth of invasion, and presence of lymphovascular and perineural invasion. However, the tumor excision margins are adequately described in almost all reports.Conclusions.The study shows that clinicians do not provide adequate clinical information when submitting a request for histopathologic examination of BCC. Similarly, pathologists write incomplete reports that lack important pathologic features. Having pre-set forms (electronic proforma) can help overcome missing information.

2019 ◽  
Vol 13 ◽  
pp. 136-139 ◽  
Author(s):  
Davin C. Ashraf ◽  
Evan Kalin-Hajdu ◽  
Marc H. Levin ◽  
Robert C. Kersten

2017 ◽  
Vol 83 (1) ◽  
pp. 94-97 ◽  
Author(s):  
André Bandiera de Oliveira Santos ◽  
Natália Martins Magacho de Andrade ◽  
Lenine Garcia Brandão ◽  
Claudio Roberto Cernea

2008 ◽  
Vol 34 (12) ◽  
pp. 1642-1651
Author(s):  
DAVID E. GEIST ◽  
MARIA GARCIA-MOLINER ◽  
MARKUS M. FITZEK ◽  
HANNAH CHO ◽  
GARY S. ROGERS

2021 ◽  
Vol 13 (2) ◽  
Author(s):  
Khairuddin Djawad ◽  
Siswanto Wahab ◽  
Airin Nurdin

Defects resulting from surgical procedure may be challenging to reconstruct depending on the size and location. In case of large defects, primary closure is often not possible and thus requires skin flap or graft. In such cases, skin flap is advantageous as it produces a similar color and texture with the surrounding tissue. Skin flap techniques such as advancement flap, rotation flap dan transposition flap are useful in closing small defects. In moderate to large-sized defects, especially in areas with high tension, a combination of more than one type of flap might be necessary. This report describes two cases of large defects on the temple and cheek following basal cell carcinoma excisional surgery which were successfully closed using a combination of rotation and advancement flaps. Both patients showed excellent functional and cosmetic outcome.


2018 ◽  
Vol 21 (1) ◽  
pp. 10-15
Author(s):  
Elena S. Snarskaya ◽  
Ibrahim Abdula

Histological variants of basal cell carcinoma (BСС) are characterized by a variety of structures depending on the location of the original tumor cells, their differentiation, the reaction of the surrounding tissue, the age of the patient, which causes a large number of histological classifications of the tumor. To evaluate the prognosis of the effectiveness of different treatment methods and the biological behavior of the ВCC, the clinical form and the corresponding histomorphological type of tumor are of great importance. Most of the primary foci of the ВCC are surface and micronodular (syn.: nodular) forms, rarely there is a scleroderm-like variant and extremely rarely fibroepithelioma of Pincus. Surface and micronodular forms of ВCC corresponding to the T1N0M0 characteristic (up to 2 cm in diameter) with a simple histological type of structure (multicentric, solidly compact) are regarded as tumors with a low risk of recurrence and progression. Materials and methods. Studying the features of the pathomorphological characteristics of the tumor and the frequency of various variants on the basis of an analysis of 223 ВCC biopsy specimens, we found that most often (54.7%) there was a solid type of tumor, less often -- superficial (12.7%), morphea (4.9% ), adenoid (10.9%), as well as ВCC with a piloidal (3.1%) and sebaceous (4.4%) differentiation. Among the biopsies analyzed in 6.8% of cases metatypic cancer was found. Conclusions: The histological structure of the tumor can determine its biological behavior and have prognostic significance. Thus, pronounced primitive angiogenesis, infiltrating growth and active stroma formation testify to tumor aggressiveness and clinically most correspond to the recurring macronodular and infiltrative clinical forms of BCC. The tumor is most aggressive in its basosquamous transformation, manifested in the emergence of two components of the tumor complex in the area of dyskeratosis and pseudoepitheliomatous hyperplasia of the epidermis: basal cell carcinoma and highly differentiated cancer, which corresponds to the formation of metatype skin cancer.


2018 ◽  
pp. 314-319 ◽  
Author(s):  
John Pyne ◽  
Esther Mint ◽  
Elizabeth Barr ◽  
Simon Clark ◽  
Ruihang Hou

Background: The depth of invasion by basal cell carcinoma (BCC) subtypes varies. Objective: To investigate BCC invasion depth variation by subtype and anatomic site. Method: A prospective consecutive case series of excised BCC from 2009 to 2014 in a single Australian clinic. Results: Descending mean depths for a total of 4,565 BCC cases by subtype were as follows: nodulocystic, 1.9 mm (n = 84, 95% CI: 1.70–2.03, P = 0.66); nodular, 1.6 mm (n = 947, 95% CI: 1.53–1.63, P < 0.0001); aggressive, 1.5 mm (n = 925, 95% CI: 1.44–1.59, P < 0.0001); superficial combined with nodular, 0.9 mm (n = 1,081, 95% CI: 0.83-0.90, P < 0.0001); and superficial, 0.3 mm (n = 1,528, 95% CI: 0.32-0.36, P < 0.0001). Deeper invasion was associated with increased chronic sunlight exposed sites. The deepest aggressive BCCs occurred on the neck with a mean depth of 1.8 mm (n = 46, 95% CI: 1.47–2.21). Conclusion: We found significant differences in the depth of invasion for BCCs by sex, subtype, and anatomic site. For BCC with characteristics matching this study, overall adequate microscopic excision depths are proposed: superficial, 1.0 mm; superficial combined with nodular, 2.0 mm; nodular, 3.0 mm; and aggressive, 3.0 mm.


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