scholarly journals Transient Hypophosphatemia: A Dangerous Event in Multiple Myeloma

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Paula Jeffs ◽  
Michelle Mangual-García ◽  
Alex González-Bóssolo ◽  
Nadyeschka Rivera-Santana
Keyword(s):  
Multiple Myeloma ◽  
Medical Treatment ◽  
American Association ◽  
Annual Scientific ◽  
Metabolic Disturbances ◽  
Phosphate Absorption ◽  
Multiple Factors ◽  
Electrolyte Disturbances

Patients with malignancies frequently experience multiple electrolyte disturbances. In multiple myeloma, hypercalcemia and hyperphosphatemia are one of the most common metabolic disturbances observed as part of pathogenesis of the disease. However, in rare occasions and during the course of the disease, many patients can develop hypophosphatemia due to multiple factors that affects the phosphate absorption and excretion. We hereby present a 56 y/o woman recently diagnosed with multiple myeloma who developed severe hypophosphatemia during medical treatment. We should note that the following manuscript was presented at the 2019 American Association of Clinical Endocrinologists (AACE) 28th Annual Scientific and Clinical Congress.

Extracapsular articulating implant to treat cranial cruciate ligament disease in a dog with multiple myeloma

2019 ◽  
Vol 7 (2) ◽  
pp. e000767
Author(s):  
Eloise Elisabeth Lhuillery ◽  
Philip Georg Witte
Keyword(s):  
Multiple Myeloma ◽  
Medical Treatment ◽  
Range Of Motion ◽  
Tibial Plateau ◽  
Cruciate Ligament ◽  
Cranial Cruciate Ligament ◽  
Mild Reduction ◽  
Cranial Cruciate Ligament Disease ◽  
Hindlimb Lameness ◽  
Malignant Neoplasia

An 11-year-old Border collie was presented for left hindlimb lameness associated with cranial cruciate ligament disease. The history included right tibial plateau levelling osteotomy performed approximately two years previously, with a subjectively good outcome. Multiple myeloma had been diagnosed approximately two months before presentation of the left hindlimb lameness. Medical treatment of multiple myeloma included glucocorticoids (prednisolone) and melphalan. Stabilisation of the left stifle was performed with the Simitri Stable in Stride extracapsular articulating implant. The dog demonstrated weightbearing on the operated limb within 24 hours following surgery. Re-examination six weeks following surgery revealed mild left hindlimb lameness, no resentment to manipulation of the left stifle, no cranial tibial thrust and a mild reduction in the range of motion. Hindlimb function was affected by various neurological events considered secondary to the malignant neoplasia; however, left stifle function was good until euthanasia 11 months following surgery.

scholarly journals Renal stone disease: causes, evaluation and medical treatment

2006 ◽  
Vol 50 (4) ◽  
pp. 823-831 ◽  
Author(s):  
Ita Pfeferman Heilberg ◽  
Nestor Schor
Keyword(s):  
Medical Treatment ◽  
Renal Stone ◽  
Salt Intake ◽  
Current Knowledge ◽  
Stone Formation ◽  
Potassium Citrate ◽  
Blood Analysis ◽  
Dietary Recommendations ◽  
Metabolic Disturbances ◽  
Mineral Density

The purpose of the present review is to provide an update about the most common risk factors or medical conditions associated with renal stone formation, the current methods available for metabolic investigation, dietary recommendations and medical treatment. Laboratory investigation of hypercalciuria, hyperuricosuria, hyperoxaluria, cystinuria, hypocitraturia, renal tubular acidosis, urinary tract infection and reduction of urinary volume is based on the results of 24-hr urine collection and a spot urine for urinary sediment, culture and pH. Blood analysis for creatinine, calcium and uric acid must be obtained. Bone mineral density has to be determined mainly among hypercalciurics and primary hyperparathyroidism has to be ruled out. Current knowledge does not support calcium restriction recommendation because it can lead to secondary hyperoxaluria and bone demineralization. Reduction of animal protein and salt intake, higher fluid intake and potassium consumption should be implemented. Medical treatments involve the use of thiazides, allopurinol, potassium citrate or other drugs according to the metabolic disturbances. The correction of those metabolic abnormalities is the basic tool for prevention or reduction of recurrent stone formation.

American Association for Bronchology 5th Annual Scientific Assembly

1997 ◽  
Vol 4 (2) ◽  
pp. 193
Author(s):  
&NA;
Keyword(s):  
American Association ◽  
Annual Scientific

Oxidant/antioxidant parameters and their relationship with medical treatment in multiple myeloma

2004 ◽  
Vol 23 (1) ◽  
pp. 47-50 ◽  
Author(s):  
Irfan Kuku ◽  
Ismet Aydogdu ◽  
Nihayet Bayraktar ◽  
Emin Kaya ◽  
Omer Akyol ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Medical Treatment ◽  
Antioxidant Parameters
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