scholarly journals Oligodendrocyte Progenitor Cells Promote Neovascularization in Glioma by Disrupting the Blood–Brain Barrier

2013 ◽  
Vol 74 (4) ◽  
pp. 1011-1021 ◽  
Author(s):  
Yujie Huang ◽  
Caitlin Hoffman ◽  
Prajwal Rajappa ◽  
Joon-Hyung Kim ◽  
Wenhuo Hu ◽  
...  
2016 ◽  
Vol 7 ◽  
Author(s):  
Natalia A. Malinovskaya ◽  
Yulia K. Komleva ◽  
Vladimir V. Salmin ◽  
Andrey V. Morgun ◽  
Anton N. Shuvaev ◽  
...  

2018 ◽  
Vol 27 (12) ◽  
pp. 1798-1808 ◽  
Author(s):  
Jyoti Gautam ◽  
Yao Yao

Stroke is a cerebrovascular disorder that affects many people worldwide. In addition to the well-established functions of astrocytes and microglia in stroke pathogenesis, pericytes also play an important role in stroke progression and recovery. As perivascular multi-potent cells and an important component of the blood–brain barrier (BBB), pericytes have been shown to exert a large variety of functions, including serving as stem/progenitor cells and maintaining BBB integrity. Here in this review, we summarize the roles of pericytes in stroke pathogenesis, with a focus on their effects in cerebral blood flow, BBB integrity, angiogenesis, immune responses, scar formation and fibrosis.


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