Abstract LB-66: Results of two phase I multicenter trials of AZD5363, an inhibitor of AKT1, 2 and 3: Biomarker and early clinical evaluation in Western and Japanese patients with advanced solid tumors .

2013 ◽  
Author(s):  
Udai Banerji ◽  
Malcolm Ranson ◽  
Jan HM Schellens ◽  
Taito Esaki ◽  
Emma Dean ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Clinical Evaluation ◽  
Japanese Patients ◽  
Advanced Solid Tumors ◽  
Two Phase ◽  
Multicenter Trials

A phase I study of resminostat in Japanese patients with advanced solid tumors

2015 ◽  
Vol 75 (6) ◽  
pp. 1155-1161 ◽  
Author(s):  
Satoru Kitazono ◽  
Yutaka Fujiwara ◽  
Shinji Nakamichi ◽  
Hidenori Mizugaki ◽  
Hiroshi Nokihara ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Phase I Study ◽  
Japanese Patients ◽  
Advanced Solid Tumors

Abstract A167: A phase I study of single-agent BEZ235 (SDS sachet), once- or twice-daily, in Japanese patients with advanced solid tumors.

2013 ◽  
Author(s):  
Koichiro Watanabe ◽  
Hironobu Minami ◽  
Satoshi Otsu ◽  
Yoshinori Hirashima ◽  
Ryotaro Morinaga ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Phase I Study ◽  
Single Agent ◽  
Japanese Patients ◽  
Advanced Solid Tumors

scholarly journals Phase I study of single-agent ribociclib in Japanese patients with advanced solid tumors

2017 ◽  
Vol 109 (1) ◽  
pp. 193-198 ◽  
Author(s):  
Toshihiko Doi ◽  
Becker Hewes ◽  
Tomoyuki Kakizume ◽  
Takeshi Tajima ◽  
Norifumi Ishikawa ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Phase I Study ◽  
Single Agent ◽  
Japanese Patients ◽  
Advanced Solid Tumors

Phase I, open-label, multi-ascending dose trial of avelumab (MSB0010718C), an anti-PD-L1 monoclonal antibody, in Japanese patients with advanced solid tumors.

2015 ◽  
Vol 33 (15_suppl) ◽  
pp. 3023-3023 ◽  
Author(s):  
Kohei Shitara ◽  
Yasuhide Yamada ◽  
Kiyotaka Yoh ◽  
Yoichi Naito ◽  
Satoru Iwasa ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Phase I ◽  
Solid Tumors ◽  
Japanese Patients ◽  
Advanced Solid Tumors ◽  
Open Label ◽  
Dose Trial

scholarly journals A Phase I, dose-finding and pharmacokinetic study of olaparib (AZD2281) in Japanese patients with advanced solid tumors*,†

2012 ◽  
Vol 103 (3) ◽  
pp. 504-509 ◽  
Author(s):  
Noboru Yamamoto ◽  
Hiroshi Nokihara ◽  
Yasuhide Yamada ◽  
Yasushi Goto ◽  
Maki Tanioka ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Pharmacokinetic Study ◽  
Japanese Patients ◽  
Dose Finding ◽  
Advanced Solid Tumors

scholarly journals Phase I study of roniciclib (BAY1000394), an oral CDK inhibitor in Japanese patients with advanced solid tumors

2016 ◽  
Vol 27 ◽  
pp. vii87-vii88
Author(s):  
Takashi Seto ◽  
Kaname Nosaki ◽  
Gen Shinoda ◽  
Kensei Hashizume ◽  
Iku Yamaguchi ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Phase I Study ◽  
Japanese Patients ◽  
Cdk Inhibitor ◽  
Advanced Solid Tumors

scholarly journals Phase I dose‐escalation study of capmatinib ( INC 280) in Japanese patients with advanced solid tumors

2019 ◽  
Vol 110 (4) ◽  
pp. 1340-1351 ◽  
Author(s):  
Taito Esaki ◽  
Fumihiko Hirai ◽  
Akitaka Makiyama ◽  
Takashi Seto ◽  
Hideaki Bando ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Japanese Patients ◽  
Advanced Solid Tumors ◽  
Dose Escalation Study
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