Abstract 4437: The relevance of aberrant FPGS splicing for ex vivo MTX resistance and clinical outcome in childhood acute lymphoblastic leukemia

Clinical Outcome ◽

Ex Vivo ◽

Lymphoblastic Leukemia ◽

The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia

Haematologica ◽

10.3324/haematol.2016.142794 ◽

2016 ◽

Vol 101 (7) ◽

pp. e291-e294 ◽

Cited By ~ 10

Author(s):

A. Wojtuszkiewicz ◽

Y. G. Assaraf ◽

M. Hoekstra ◽

R. Sciarrillo ◽

G. Jansen ◽

...

Keyword(s):

Clinical Outcome ◽

Ex Vivo ◽

Lymphoblastic Leukemia ◽

Folylpolyglutamate Synthetase ◽

Methotrexate Resistance

Acute Leukemias - Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ◽

Correlation of In Vitro Drug Resistance Assessed by the MTT Assay with Long Term Clinical Outcome in Childhood Acute Lymphoblastic Leukemia

10.1007/978-3-642-76591-9_53 ◽

1992 ◽

pp. 332-337

Author(s):

R. Pieters ◽

D. R. Huismans ◽

A. H. Loonen ◽

K. Hählen ◽

A. van der Does-van den Berg ◽

...

Keyword(s):

Drug Resistance ◽

Clinical Outcome ◽

Mtt Assay ◽

Lymphoblastic Leukemia ◽

Inheritance and clinical outcome in childhood acute lymphoblastic leukemia

Leukemia Research ◽

10.1016/j.leukres.2009.01.028 ◽

2009 ◽

Vol 33 (7) ◽

pp. 889-890

Author(s):

Krzysztof Jamroziak ◽

Tadeusz Robak

Keyword(s):

Clinical Outcome ◽

Lymphoblastic Leukemia ◽

Bcl-2 family members in childhood acute lymphoblastic leukemia: relationships with features at presentation, in vitro and in vivo drug response and long-term clinical outcome

Leukemia ◽

10.1038/sj.leu.2401529 ◽

1999 ◽

Vol 13 (10) ◽

pp. 1574-1580 ◽

Cited By ~ 46

Author(s):

GS Salomons ◽

LA Smets ◽

M Verwijs-Janssen ◽

AAM Hart ◽

EG Haarman ◽

...

Keyword(s):

Clinical Outcome ◽

Drug Response ◽

Lymphoblastic Leukemia ◽

Family Members ◽

The anti-asparagines antibodies correlate withl-asparagines activity and may affect clinical outcome of childhood acute lymphoblastic leukemia

Leukemia & Lymphoma ◽

10.1080/10428190701292049 ◽

2007 ◽

Vol 48 (5) ◽

pp. 931-936 ◽

Cited By ~ 50

Author(s):

Beata Zalewska-Szewczyk ◽

Witalij Andrzejewski ◽

Wojciech Młynarski ◽

Krystyna Jędrychowska-Dańska ◽

Henryk Witas ◽

...

Keyword(s):

Clinical Outcome ◽

Lymphoblastic Leukemia ◽

Functional C3435T polymorphism of MDR1 gene: an impact on genetic susceptibility and clinical outcome of childhood acute lymphoblastic leukemia

European Journal Of Haematology ◽

10.1111/j.1600-0609.2004.00228.x ◽

2004 ◽

Vol 72 (5) ◽

pp. 314-321 ◽

Cited By ~ 136

Author(s):

Krzysztof Jamroziak ◽

Wojciech Młynarski ◽

Ewa Balcerczak ◽

Magda Mistygacz ◽

Joanna Treliǹska ◽

...

Keyword(s):

Clinical Outcome ◽

Genetic Susceptibility ◽

Lymphoblastic Leukemia ◽

Mdr1 Gene ◽

C3435t Polymorphism

Persistence of E2A/PBX1 transcripts in t(1;19) childhood acute lymphoblastic leukemia: Correlation with chemotherapy intensity and clinical outcome

Leukemia Research ◽

10.1016/0145-2126(95)00115-8 ◽

1996 ◽

Vol 20 (5) ◽

pp. 441-443 ◽

Cited By ~ 14

Author(s):

Carlo Lanza ◽

Enrico Gottardi ◽

Gianluca Gaidano ◽

Claudia Vivenza ◽

Adele Parziale ◽

...

Keyword(s):

Clinical Outcome ◽

Lymphoblastic Leukemia ◽

Expression of the Multidrug Transporter P-glycoprotein is Highly Correlated with Clinical Outcome in Childhood Acute Lymphoblastic Leukemia: Results of a Long-Term Prospective Study

Leukemia & Lymphoma ◽

10.1080/10428190290006080 ◽

2002 ◽

Vol 43 (2) ◽

pp. 309-314 ◽

Cited By ~ 20

Author(s):

Catharina Dhooge ◽

Barbara De Moerloose ◽

Geneviève Laureys ◽

Alice Ferster ◽

Dirk De Bacquer ◽

...

Keyword(s):

Clinical Outcome ◽

Prospective Study ◽

Lymphoblastic Leukemia ◽

Multidrug Transporter ◽

P Glycoprotein ◽

Highly Correlated

Acute Leukemias - Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ◽

Karyotype, Immunophenotype, and Clinical Outcome: Correlations in Childhood Acute Lymphoblastic Leukemia

10.1007/978-3-642-71213-5_88 ◽

1987 ◽

pp. 504-508

Author(s):

M. J. Gregoire ◽

M. A. Peeters ◽

M. C. Bene ◽

P. Bordigoni ◽

G. Faure ◽

...

Keyword(s):

Clinical Outcome ◽

Lymphoblastic Leukemia ◽

Ex vivo resistance in childhood acute lymphoblastic leukemia: Correlations between BCRP, MRP1, MRP4 and MRP5 ABC transporter expression and intracellular methotrexate polyglutamate accumulation

Leukemia Research ◽

10.1016/j.leukres.2019.02.008 ◽

2019 ◽

Vol 79 ◽

pp. 45-51 ◽

Cited By ~ 3

Author(s):

Adrian C. Jaramillo ◽

Jacqueline Cloos ◽

Clara Lemos ◽

Ronald W. Stam ◽

Gertjan J.L. Kaspers ◽

...

Keyword(s):

Abc Transporter ◽

Ex Vivo ◽

Lymphoblastic Leukemia ◽

Methotrexate Polyglutamate ◽

Transporter Expression