Abstract 4530: Tissue distribution, excretion and pharmacokinetics of the environmental pollutant and the tobacco smoke constituent dibenzo[a,l]pyrene in mice

2015 ◽  
Author(s):  
Kun-Ming Chen ◽  
Yuan-Wan Sun ◽  
Cesar Aliaga ◽  
Alaa Awad ◽  
Krishne Gowda ◽  
...  
Keyword(s):  
Tissue Distribution ◽  
Tobacco Smoke ◽  
Environmental Pollutant

scholarly journals Mechanisms of oral carcinogenesis induced by dibenzo[a,l]pyrene: An environmental pollutant and a tobacco smoke constituent

2013 ◽  
Vol 133 (6) ◽  
pp. 1300-1309 ◽  
Author(s):  
Kun-Ming Chen ◽  
Joseph B. Guttenplan ◽  
Shang-Min Zhang ◽  
Cesar Aliaga ◽  
Timothy K. Cooper ◽  
...  
Keyword(s):  
Tobacco Smoke ◽  
Environmental Pollutant ◽  
Oral Carcinogenesis

scholarly journals Tissue Distribution, Excretion and Pharmacokinetics of the Environmental Pollutant Dibenzo[def,p]chrysene in Mice

2015 ◽  
Vol 28 (7) ◽  
pp. 1427-1433 ◽  
Author(s):  
Yuan-Wan Sun ◽  
Karam El-Bayoumy ◽  
Cesar Aliaga ◽  
Alaa S. Awad ◽  
Krishne Gowda ◽  
...  
Keyword(s):  
Tissue Distribution ◽  
Environmental Pollutant

Impact of Moderate Prenatal Alcohol Exposure on Problem Behaviors in Preschool and School Children

2014 ◽  
Vol 46 (2) ◽  
pp. 89-100 ◽  
Author(s):  
Manuela Pfinder ◽  
Stefan Liebig ◽  
Reinhold Feldmann
Keyword(s):  
Problem Behaviors ◽  
Tobacco Smoke ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Smoke Exposure ◽  
Low Ses ◽  
German Health ◽  
Kiggs Study ◽  
Strengths And Difficulties ◽  
Prenatal Alcohol

Data on the relation between moderate prenatal alcohol exposure (PAE) and behavioral disorders are inconsistent, and this raises new questions. We examined (1) the association between moderate PAE and problem behaviors and (2) whether these associations differed by levels of socioeconomic status (SES), fetal smoke exposure, or exposure to environmental tobacco smoke (ETS). Data were taken from the German Health Interview and Examination Survey for Children and Adolescents (KiGGS) study. Parents evaluated children’s behaviors using the Strengths and Difficulties Questionnaire (SDQ). Results showed a slight, but insignificant, increase of problem behaviors in children with moderate PAE. In 3- to 6-year-olds, PAE had a stronger effect on hyperactivity/inattention in combination with fetal smoke exposure (odds ratio = 2.82), than did PAE alone. Effects were not stronger in low-SES children, but they were stronger in children with ETS. We conclude that moderate PAE might have adverse effects on neurodevelopment, with stronger effects in disadvantaged populations. To confirm our preliminary findings, further research should be conducted.

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