Abstract 1608: CD122-selective IL-2/anti-IL-2 complexes reduce regulatory T cell function and promote CD8+T cell polyfunctionality for durable ovarian cancer immunotherapy

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Sri Lakshmi Pandeswara ◽  
Aijie Liu ◽  
Curtis A. Clark ◽  
Alvaro S. Padron ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
T Cell ◽  
Cancer Immunotherapy ◽  
Regulatory T Cell ◽  
Cell Function ◽  
Cd8 T Cell ◽  
T Cell Function

scholarly journals Recovery of CD8+ T-Cell Function During Systemic Chemotherapy in Advanced Ovarian Cancer

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pp. 7000-7006 ◽  
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Sharon Coleman ◽  
Aled Clayton ◽  
Malcolm D. Mason ◽  
Bharat Jasani ◽  
Malcolm Adams ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
T Cell ◽  
Systemic Chemotherapy ◽  
Cell Function ◽  
Advanced Ovarian Cancer ◽  
Cd8 T Cell ◽  
T Cell Function

scholarly journals Plasma Gelsolin Inhibits CD8+ T-cell Function and Regulates Glutathione Production to Confer Chemoresistance in Ovarian Cancer

2020 ◽  
Vol 80 (18) ◽  
pp. 3959-3971 ◽  
Author(s):  
Meshach Asare-Werehene ◽  
Laudine Communal ◽  
Euridice Carmona ◽  
Youngjin Han ◽  
Yong Sang Song ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
T Cell ◽  
Cell Function ◽  
Cd8 T Cell ◽  
Plasma Gelsolin ◽  
T Cell Function

scholarly journals Aberrant upregulation of PDK1 in ovarian cancer cells impairs CD8+ T cell function and survival through elevation of PD-L1

2019 ◽  
Vol 8 (11) ◽  
pp. 1659092 ◽  
Author(s):  
Jing-Jing Wang ◽  
Michelle K. Siu ◽  
Yu-Xin Jiang ◽  
Thomas H. Leung ◽  
David W. Chan ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
T Cell ◽  
Cancer Cells ◽  
Cell Function ◽  
Cd8 T Cell ◽  
Ovarian Cancer Cells ◽  
T Cell Function
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