Abstract 2139: Enabling cancer drug target discovery through genome-scale identification of synthetic lethal paralog pairs

2021 ◽  
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Phoebe C. Parrish ◽  
James D. Thomas ◽  
Shriya Kamlapurkar ◽  
Robert K. Bradley ◽  
Alice H. Berger
Keyword(s):  
Drug Target ◽  
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Drug Target Discovery ◽  
Target Discovery ◽  
Synthetic Lethal ◽  
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scholarly journals Functional Genomics for Cancer Drug Target Discovery

Cancer Cell ◽  
2020 ◽  
Vol 38 (1) ◽  
pp. 31-43 ◽  
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Benjamin Haley ◽  
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Keyword(s):  
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Vol 19 (1) ◽  
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Levi A. Garraway ◽  
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Exposing oncogenic dependencies for cancer drug target discovery and validation using RNAi

2003 ◽  
Vol 13 (4) ◽  
pp. 293-300 ◽  
Author(s):  
Quinn L Deveraux ◽  
Pedro Aza-Blanc ◽  
Klaus W Wagner ◽  
Dirk Bauerschlag ◽  
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scholarly journals MEDICI: Mining Essentiality Data to Identify Critical Interactions for Cancer Drug Target Discovery and Development

PLoS ONE ◽  
2017 ◽  
Vol 12 (1) ◽  
pp. e0170339 ◽  
Author(s):  
Sahar Harati ◽  
Lee A. D. Cooper ◽  
Josue D. Moran ◽  
Felipe O. Giuste ◽  
Yuhong Du ◽  
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scholarly journals Application of genomics and proteomics in drug target discovery

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pp. 198-204 ◽  
Author(s):  
H.M. Zhang ◽  
Z.R. Nan ◽  
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X.H. Liu ◽  
Y. Sun
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scholarly journals Metabolomics in Drug Target Discovery

2011 ◽  
Vol 76 (0) ◽  
pp. 235-246 ◽  
Author(s):  
J. D. Rabinowitz ◽  
J. G. Purdy ◽  
L. Vastag ◽  
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Keyword(s):  
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