Abstract 1534: MEDI5083, a novel CD40L-Fc fusion protein, activates the CD40 pathway on antigen presenting cells and promotes a robust anti-tumor immune response in a B16F10 murine tumor model

2019 ◽  
Author(s):  
Sean Turman ◽  
Kelly McGlinchey ◽  
YaYa Wang ◽  
Deepali Malhotra ◽  
Ronald Herbst ◽  
...  
Keyword(s):  
Immune Response ◽  
Fusion Protein ◽  
Tumor Model ◽  
Antigen Presenting Cells ◽  
Murine Tumor ◽  
Murine Tumor Model ◽  
Fc Fusion Protein ◽  
Antigen Presenting

scholarly journals Investigation of HIFU-induced anti-tumor immunity in a murine tumor model

2007 ◽  
Vol 5 (1) ◽  
pp. 34 ◽  
Author(s):  
Zhenlin Hu ◽  
Xiao Yang ◽  
Yunbo Liu ◽  
Georgy N Sankin ◽  
Eric C Pua ◽  
...  
Keyword(s):  
Tumor Immunity ◽  
Tumor Model ◽  
Murine Tumor ◽  
Murine Tumor Model

scholarly journals A Cu(ii) complex targeting the translocator protein: in vitro and in vivo antitumor potential and mechanistic insights

2017 ◽  
Vol 53 (1) ◽  
pp. 134-137 ◽  
Author(s):  
D. Montagner ◽  
B. Fresch ◽  
K. Browne ◽  
V. Gandin ◽  
A. Erxleben
Keyword(s):  
Tumor Model ◽  
Translocator Protein ◽  
Tumor Mass ◽  
Cu Complex ◽  
Murine Tumor ◽  
Murine Tumor Model ◽  
Antitumor Potential

A Cu complex targeting the translocator protein induces a 98% reduction of tumor mass in a murine tumor model.

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