An Alternative Diagnostic Test for Active Ménière’s Disease and Cochlear Hydrops Using High-Pass Noise Masked Responses: The Complex Amplitude Ratio

2007 ◽  
Vol 12 (6) ◽  
pp. 359-370 ◽  
Author(s):  
Manuel Don ◽  
Betty Kwong ◽  
Chiemi Tanaka
Keyword(s):  
Diagnostic Test ◽  
Amplitude Ratio ◽  
Meniere’S Disease ◽  
Complex Amplitude ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Ménière's Disease ◽  
High Pass

Electrocochleography in Retrosigmoid Vestibular Nerve Section for Intractable Vertigo Caused by Meniere's Disease

1997 ◽  
Vol 116 (6) ◽  
pp. 593-596 ◽  
Author(s):  
Wesley W. O. Krueger ◽  
Ian S. Storper
Keyword(s):  
Amplitude Ratio ◽  
Meniere’S Disease ◽  
Vestibular Nerve ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Nerve Section ◽  
Summating Potential ◽  
Ménière's Disease

Interest in electrocochleography has increased in recent years because of the discovery of an elevated summating potential to action potential amplitude ratio (SP/AP ratio) in patients with endolymphatic hydrops caused by Meniere's disease or perilymph fistula. It was the purpose of this investigation to determine whether the intraoperative SP/AP ratio will decrease after vestibular nerve section in patients with intractable Meniere's disease. Fourteen patients with medically intractable classic Meniere's disease underwent retrosigmoid vestibular nerve section. Intraoperative transtympanic electrocochleography was performed with alternating click stimuli presented at 95 dB HL. In all patients the SP/AP ratio was recorded before the skin incision (“baseline” condition) and after the dura was closed (“closing” condition). Statistical analysis was applied to the recorded data. In 11 (79%) patients, the SP/AP ratio was found to be elevated above 0.30 in the baseline state. In 13 (93%) patients, the SP/AP ratio decreased more than 25% after the nerve was sectioned. These results were highly statistically significant (p < 0.001). We conclude that the SP/AP ratio does decrease in patients with Meniere's disease after undergoing retrosigmoid vestibular nerve section and offer a possible explanation. (Otolaryngol Head Neck Surg 1997;116:593–6.)

Use of electrocochleography to monitor antigenic challenge in Meniere's disease

1992 ◽  
Vol 107 (6_part_1) ◽  
pp. 733-737 ◽  
Author(s):  
George J. Viscomi ◽  
Dennis I. Bojrab
Keyword(s):  
Hearing Loss ◽  
Amplitude Ratio ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Subjective Symptoms ◽  
Menière's Disease ◽  
Antigenic Challenge ◽  
Ménière's Disease

Allergy has been reported as a cause of Meniere's disease. King et al. have established the validity of the provocative food test (PFT) for the diagnosis of food allergy. When the PFT is used to fest patients with Meniere's disease, the test is considered positive If the patient develops aural fullness, hearing loss, increased tinnitus, or dizziness during challenge with the offending food and relief of these symptoms during neutralization. Ferraro et al. have shown that electrocochleography (ECoG) provides an objective indication of subjective symptoms In Meniere's disease by demonstrating an Increased SP/AP amplitude ratio when the symptoms of aural fullness and hearing loss are present. We present several patients with Meniere's disease In whom measurement of the SP/AP amplitude ratio was compared with symptom production during antigenic challenge and neutralization.

scholarly journals Clinical evaluation of a new electrocochleography recording electrode

2020 ◽  
Author(s):  
Mostafa Eyvazi ◽  
Akram Pourbakht ◽  
Seyyed Jalal Sameni ◽  
Mohammad Kamali
Keyword(s):  
Action Potential ◽  
Amplitude Ratio ◽  
Normal Subjects ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Ménière's Disease ◽  
The Mean

Background and Aim: Electrocochleography is one of the most practically used tests in app­roaching Meniere's disease (MD). To record reli­able response components, the type of applied electrode is of particular importance. The TIP-trode is an appropriate electrode due to its user-friendliness. Gutter electrode can be used in more than 100 subject. This study aimed to com­pare the results of the Electrocochleography (ECochG) test responses using TIP-trode and the Gutter electrode. Methods: This cross-sectional study was perfor­med on 20 normal subjects and 20 patients with MD, who referred to the Audiology Clinic of Iran University of Medical Sciences. The ECochG response components were randomly recorded with TIP-trode and Gutter-electrode consecu­tively, and then statistical analysis was accomp­lished. Results: The mean impedance, action potential, and summation potential amplitudes were not significantly different between normal subjects and people with MD by using two types of elec­trodes. Moreover, the mean scores of summation potential/action potential (SP/AP) ratio of the Gutter electrode were higher than that of the TIP-trod. The mean SP/AP ratio between two types of electrodes was statistically significant differences in normal subjects (p = 0.027) and in MD group (p = 0.009). Conclusion: We demonstrated that the utili­zation of the Gutter electrode in ECochG assess­ments was considerably effective and beneficial. It can significantly reduce expenses and be app­lied in clinical settings. It’s also recommended that 47.22% mean SP/AP amplitude ratio to be considered as upper limit of normality by using the Gutter electrode. Keywords: Electrocochleography; Meniere's disease; Gutter electrode; TIP-trode; impedance  

Interpretation of Electrocochleography in Meniere's Disease and Normal Subjects

1992 ◽  
Vol 101 (6) ◽  
pp. 496-500 ◽  
Author(s):  
Kathleen C. M. Campbell ◽  
Lee A. Harker ◽  
Paul J. Abbas
Keyword(s):  
Amplitude Ratio ◽  
Hearing Threshold ◽  
Normal Subjects ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Summating Potential ◽  
Ménière's Disease

Electrocochleographic recordings were obtained from 20 subjects with normal hearing and 10 subjects with Meniere's disease by using an eardrum electrode. Stimuli included clicks and 6,000-Hz tone bursts. Results were not significantly different between the two groups for summating potential (SP) amplitude, action potential (AP) amplitude, or the SP/AP amplitude ratio. Interpreting the results in light of symptoms on the date of assessment or hearing threshold did not appear to improve separation between the two groups. Various SP/AP amplitude ratio criteria have been proposed in order to separate normal patients from those with Meniere's disease. Applying these proposed criteria to our data did not successfully separate the two groups.

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