Regional Cerebral Blood Flow in Multiple Sclerosis Measured by Single Photon Emission Tomography with Technetium-99m Hexamethyl-propyleneamine Oxime

1993 ◽  
Vol 33 (2) ◽  
pp. 163-167 ◽  
Author(s):  
Jan Lycke ◽  
Carsten Wikkelsö ◽  
Ann-Christine Bergh ◽  
Lars Jacobsson ◽  
Oluf Andersen
1991 ◽  
Vol 158 (4) ◽  
pp. 558-562 ◽  
Author(s):  
Ken Wilson ◽  
David Bowen ◽  
Paul Francis ◽  
Philippa Tyrrell

Patients with Alzheimer disease (AD) had reduced regional cerebral blood flow (rCBF) in the posterior parietotemporal region compared with controls, as determined with technetium-99m hexamethyl propyleneamine oxime and single photon emission tomography. Central cholinergic stimulation with physostigmine produced a focal increase in rCBF in the posterior parietotemporal region in the patients with AD but not in controls.


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