In situ Detection of Epstein-Barr Virus Markers in Nasopharyngeal Carcinoma Patients

Oncology ◽  
1989 ◽  
Vol 46 (5) ◽  
pp. 310-317 ◽  
Author(s):  
Maria Li Lung ◽  
Kwok Hung Chan ◽  
Wai Pang Lam ◽  
Sio Kei Kou ◽  
Damon Choy ◽  
...  

Cancer ◽  
2017 ◽  
Vol 124 (2) ◽  
pp. 434-435 ◽  
Author(s):  
Vivian Wai Yan Lui ◽  
Ka-Fai To ◽  
Kwok-Wai Lo


Cancer ◽  
2017 ◽  
Vol 124 (2) ◽  
pp. 435-436 ◽  
Author(s):  
Siraj M. Ali ◽  
Jeffrey S. Ross ◽  
Kai Wang


2016 ◽  
Vol 25 (4) ◽  
pp. 304-309 ◽  
Author(s):  
Alicia Rumayor Piña ◽  
Harim Tavares dos Santos ◽  
Roman Carlos ◽  
Albina Altemani ◽  
Oslei Paes de Almeida

Background. Nasopharyngeal carcinoma (NPC) is highly associated with Epstein-Barr virus (EBV), particularly the undifferentiated nonkeratinizing subtype. Prevalence of EBV in NPC in countries such as Guatemala and Brazil has not been studied. Methods. We analyzed 19 cases of NPC, 11 from Guatemala and 8 from Brazil, for the presence of EBV by in situ hybridization and immunohistochemistry. Additionally, 19 hyperplastic adenoids from children were analyzed for EBV by in situ hybridization, 12 from Guatemala and 7 from Brazil. Results. All the NPC cases from Guatemala and 5 from Brazil were of the undifferentiated nonkeratinizing type. EBV-negative cases comprised 2 keratinizing NPC and 1 differentiated nonkeratinizing NPC. All undifferentiated nonkeratinizing NPC from both samples showed intense positivity for EBER, while LMP-1 only focally and scarcely expressed. EBER was positive in 75% and 43% of the adenoids from Guatemala and Brazil, respectively. Conclusions. All undifferentiated nonkeratinizing NPC irrespective of origin from Guatemala or Brazil were highly associated with EBV.





Author(s):  
Hayriye Tatlı Doğan ◽  
Aydan Kılıçarslan ◽  
Nuran Sungu ◽  
Mehmet Doğan ◽  
Gaye Güler Tezel ◽  
...  


2006 ◽  
Vol 134 (4) ◽  
pp. 639-645 ◽  
Author(s):  
Kazunari Nakao ◽  
Masato Mochiki ◽  
Ken-Ichi Nibu ◽  
Masashi Sugasawa ◽  
Hiroshi Uozaki


2014 ◽  
Vol 05 (06) ◽  
pp. 517-522 ◽  
Author(s):  
Ameera A. M. Adam ◽  
Nazik E. Abdullah ◽  
Lamyaa A. M. El Hassan ◽  
Elwaleed M. Elamin ◽  
Muntaser E. Ibrahim ◽  
...  


Author(s):  
P. G. MURRAY ◽  
G. NIEDOBITEK ◽  
E. KREMMER ◽  
F. GRÄSSER ◽  
G. M. REYNOLDS ◽  
...  


1998 ◽  
Vol 124 (1) ◽  
pp. 53-57 ◽  
Author(s):  
Jan-Show Chu ◽  
Chung-Chung Chen ◽  
King-Jen Chang


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