Seasonal Variation of the Conjunctival Provocation Test, Total and Specific IgE in Children with Birch Pollen Allergy

1990 ◽  
Vol 92 (3) ◽  
pp. 306-308 ◽  
Author(s):  
Christian Möller ◽  
Said Elsayed
Keyword(s):  
Seasonal Variation ◽  
Birch Pollen ◽  
Pollen Allergy ◽  
Provocation Test ◽  
Specific Ige ◽  
Conjunctival Provocation Test ◽  
Birch Pollen Allergy

scholarly journals Component-Resolved Diagnosis in Pediatrics

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Ole D. Wolthers
Keyword(s):  
Allergic Disease ◽  
Birch Pollen ◽  
Pollen Allergy ◽  
Cost Benefit ◽  
Specific Ige ◽  
Component Resolved Diagnosis ◽  
Birch Pollen Allergy ◽  
Traditional Work ◽  
Diagnostic Work ◽  
Work Up

Component resolved diagnosis is a new concept in the investigation of pediatric allergic disease. The aim of the present paper is to review the available data on component resolved diagnosis with respect to implications for investigation of children with allergic disease. In most conditions head-to-head comparisons of component resolved diagnosis with traditional IgE testing have not been performed. Rather than alternatives the molecular methods should be seen as adjuncts to the cheaper traditional specific IgE tests. It may be appropriate to determine IgE antibodies to components as part of the diagnostic work-up in selected cases of peanut and birch pollen allergy and in hymenoptera allergy. However, cost benefit analyses of component resolved diagnosis compared with traditional work-up of allergy are needed. Prospectively planned protocols for assessment of the extent to which component resolved diagnosis may be able to improve the selection of children to immunotherapy and, thus, the efficacy of immunotherapy, are needed. Finally, studies of component resolved diagnosis with microarray technology in screening panels with hundreds of components should be undertaken before it can be determined to which extent such panel screening, if at all, may be helpful in children.

scholarly journals Birch pollen allergy in Europe

Allergy ◽  
2019 ◽  
Author(s):  
T. Biedermann ◽  
L. Winther ◽  
S. J. Till ◽  
P. Panzner ◽  
A. Knulst ◽  
...  
Keyword(s):  
Birch Pollen ◽  
Pollen Allergy ◽  
Birch Pollen Allergy

scholarly journals Patching it together: epicutaneous vaccination with heat-labileEscherichia colitoxin against birch pollen allergy

Allergy ◽  
2016 ◽  
Vol 72 (1) ◽  
pp. 5-8 ◽  
Author(s):  
S. S. Killingbeck ◽  
M. Q. Ge ◽  
A. Haczku
Keyword(s):  
Birch Pollen ◽  
Pollen Allergy ◽  
Birch Pollen Allergy

Potential Differences between Local and Systemic Allergic Rhinitis Induced by Birch Pollen

2020 ◽  
Vol 181 (11) ◽  
pp. 831-838
Author(s):  
Andrzej Bozek ◽  
Jolanta Zalejska Fiolka ◽  
Anna Krajewska Wojtys ◽  
Beata Galuszka ◽  
Anna Cudak
Keyword(s):  
Allergic Rhinitis ◽  
Birch Pollen ◽  
Provocation Test ◽  
Basophil Activation Test ◽  
Specific Ige ◽  
Immunological Parameters ◽  
Local Allergic Rhinitis ◽  
Before And After ◽  
Intermittent Allergic Rhinitis ◽  
Bet V1

<b><i>Introduction:</i></b> Different endotypes of rhinitis are known, but its pathomechanism has not been conclusively established. For example, the precise difference between systemic allergic rhinitis (SAR) and local allergic rhinitis (LAR) is still being checked. Comparison of patients with LAR and with allergies to birch of those with intermittent allergic rhinitis, same allergy, or with non-allergic rhinitis (NAR) was the purpose of this study. <b><i>Methods:</i></b> Twenty-six patients with LAR, 18 with SAR and allergy to birch, and 21 with NAR were included. Patients who met the inclusion criteria were selected to undergo the following procedures at baseline: medical examinations, nasal provocation test (NPT), detection of nasal-specific IgE to birch as well as basophil activation test (BAT). All immunological parameters were detected before and after NPT. <b><i>Results:</i></b> Concentration of nasal IgE to Bet v1 increased comparably in the LAR and SAR groups after NPT to birch as follows: in 21 (81%) patients with LAR, 14 (78%) with SAR, and in everyone in the NAR group. Serum concentration of allergen-specific IgE to Bet v1 increased significantly from a median of 20.7 (25–75% interval: 11.2–35.6) IU/mL to 29.9 (13.6–44.1) (<i>p</i> = 0.028) after NPT in patients with SAR. Allergen-specific IgE to Bet v1 was absent in all patients with LAR and NAR before and after NPT. BAT with Bet v1 was positive in 22 (85%) patients with LAR, in 14 (78%) with SAR, and 2 (9.5%) with NAR. <b><i>Conclusion:</i></b> These obtained data suggest there are no potential mechanisms that could explain LAR compared to SAR.

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