Lipid Metabolism in Patients with Chronic Renal Failure in the Predialytic Phase

Author(s):  
P. -O. Attman ◽  
A. Gustafson ◽  
P. Alaupovic ◽  
C. S. Wang

1993 ◽  
Vol 22 (1) ◽  
pp. 158-163 ◽  
Author(s):  
Mohammad Akmal ◽  
Stephen Perkins ◽  
Sidika E. Kasim ◽  
Ha-Young Oh ◽  
Miroslaw Smogorzewski ◽  
...  


Nephrology ◽  
2002 ◽  
Vol 7 (3) ◽  
pp. 115-120 ◽  
Author(s):  
Enyioma N Obineche ◽  
Michael PT Gillett ◽  
Abdishakur Abdulle ◽  
Mustapha Sulaiman ◽  
Mona Al-Rokhaimi


2003 ◽  
Vol 89 (4) ◽  
pp. 491-497 ◽  
Author(s):  
Shu-Tzu Chen ◽  
Sheng-Jeng Peng ◽  
Jiun-Rong Chen

The objective of the present experiment was to examine the effect of substituting different quantities of soyabean protein for casein on renal function and lipid metabolism in rats with chronic renal failure induced by a five-sixths nephrectomy. Experimental animals were subjected to a nephrectomy and fed either casein or soyabean protein (200 or 100 g/kg diet). The diets were isoenergetic with identical fat, Na, K and P contents. Rats ingesting 200 g casein/kg diet showed a significantly (P<0·05) accelerated course of chronic renal failure, while the soyabean-protein groups showed retarded progression of the experimentally induced renal disease and hypercholesterolaemic effects. Rats in the low-soyabean-protein diet (100 g/kg) also demonstrated increased serum albumin and decreased serum triacylglycerol, total cholesterol concentrations and blood urea-N; however, the low-casein diet significantly (P<0·05) increased serum triacylglycerol. Results of the present study show that the replacement of casein by soyabean protein was related to the rate of progression of renal failure and improvement in lipid profiles in serum of five-sixths nephrectomized rats.









1990 ◽  
Vol 37 (3) ◽  
pp. 854-858 ◽  
Author(s):  
Mohammad Akmal ◽  
Sidika E. Kasim ◽  
Amin R. Soliman ◽  
Shaul G. Massry




Author(s):  
N. V. Demikhova

A total of 289 patients with chronic renocardiac syndrome, 204 of them with chronic glomerulonephritis and 85 diabetic nephropathy. The worsening of the lipid metabolism, depending on the degree of chronic renal failure (CRF), I noted in the degree of CKD, manifested increased low density lipoprotein (LDL) of 1.22 times (p=0.004), triglycerides (p=0.02), atherogenicity index (p<0.0001) and decreased high-density lipoprotein (HDL) cholesterol (p<0.001). The coefficient of LDL / HDL ratio was greatest in patients with CRF I, which indicates the most intense pro-atherogenic processes in these patients. The biological role of education lipoprotein immune complexes (LPIC) is confirmed by us revealed a statistically significant negative correlation between the ratio and the atherogenic LDL IgG (r=- 0,3; p=0.04), and LDL atherogenic factor IgM (r=-0,46, p=0.01) in patients with chronic renal failure group 1. A statistically significant negative correlation between daily proteinuria and LDL IgG, LDL IgM (r=-0,3; p=0,005; r=-0,4; p=0.004, respectively), which suggests the assumption of our damaging effect LPIC on the renal glomerulus.



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