General Characteristics of Enterovirus 70

2015 ◽  
pp. 345-358 ◽  
Author(s):  
Shudo Yamazaki ◽  
Kikuko Miyamura
Keyword(s):  
Enterovirus 70

Evolution of enterovirus 70 in nature: All isolates were recently derived from a common ancestor

1986 ◽  
Vol 89 (1-4) ◽  
pp. 1-14 ◽  
Author(s):  
K. Miyamura ◽  
M. Tanimura ◽  
N. Takeda ◽  
R. Kono ◽  
S. Yamazaki
Keyword(s):  
Common Ancestor ◽  
Enterovirus 70

scholarly journals Monoclonal anti-idiotypes induce neutralizing antibodies to enterovirus 70 conformational epitopes.

1992 ◽  
Vol 66 (10) ◽  
pp. 5744-5751 ◽  
Author(s):  
J A Wiley ◽  
J Hamel ◽  
B R Brodeur
Keyword(s):  
Neutralizing Antibodies ◽  
Conformational Epitopes ◽  
Enterovirus 70

ENTEROVIRUS 70 HAEMORRHAGIC CONJUNCTIVITIS IN ZÄIRE, 1981 VERSUS 1972

The Lancet ◽  
1981 ◽  
Vol 318 (8254) ◽  
pp. 1054-1055 ◽  
Author(s):  
J. Desmyter ◽  
J. Colaert ◽  
K. Maertens ◽  
T. Muyembe
Keyword(s):  
Enterovirus 70

Neurovirulence of Enterovirus 70 in Monkeys

2015 ◽  
pp. 359-371 ◽  
Author(s):  
Nobuyuki Uchida
Keyword(s):  
Enterovirus 70

Rapid Immunofluorescence Diagnosis of Acute Hemorrhagic Conjunctivitis Caused by Enterovirus 70

Intervirology ◽  
1983 ◽  
Vol 20 (1) ◽  
pp. 19-22 ◽  
Author(s):  
S.R. Pal ◽  
Gy. Szücs ◽  
J.L. Melnick
Keyword(s):  
Acute Hemorrhagic Conjunctivitis ◽  
Enterovirus 70

Electromyographic observations in enterovirus 70 disease

1983 ◽  
Vol 56 (3) ◽  
pp. S193-S194
Author(s):  
P.N. Wadia ◽  
N.H. Wadia ◽  
S.M. Katrak ◽  
V.P. Misra
Keyword(s):  
Enterovirus 70

scholarly journals Binding to Decay-Accelerating Factor Is Not Required for Infection of Human Leukocyte Cell Lines by Enterovirus 70

2004 ◽  
Vol 78 (6) ◽  
pp. 2674-2681 ◽  
Author(s):  
Alain Haddad ◽  
M. Reza Nokhbeh ◽  
David A. Alexander ◽  
Sandra J. Dawe ◽  
Christine Grisé ◽  
...  
Keyword(s):  
Cell Lines ◽  
Hela Cells ◽  
Human Leukocyte ◽  
Myeloid Cell ◽  
Surface Expression ◽  
Virus Binding ◽  
Decay Accelerating Factor ◽  
The Central Nervous System ◽  
Enterovirus 70

ABSTRACT Enterovirus 70 (EV70) is one of several human enteroviruses that exhibit a propensity for infecting the central nervous system (CNS). The mechanisms by which neurotropic enteroviruses gain access to and invade the CNS are poorly understood. One possibility is that circulating leukocytes become infected and carry neurotropic enteroviruses to the CNS. We examined the ability of EV70 to infect cell lines derived from lymphoid, myeloid, and monocytic lineages. Most leukocyte cell lines tested bound radiolabeled EV70 and were permissive for EV70 replication, suggesting that EV70, in contrast to other enteroviruses, has an in vitro tropism that includes lymphoid, monocytic, and myeloid cell lines. For some of the cell lines, virus binding and infection correlated with surface expression of decay-accelerating factor (DAF), an attachment protein for EV70 on HeLa cells. However, EV70 also adsorbed to and infected cell lines that expressed little or no DAF. In contrast to what was observed for HeLa cells, neither DAF-specific monoclonal antibodies nor phosphatidylinositol-specific phospholipase C treatment inhibited EV70 binding to permissive leukocyte cell lines, and antibody blockade of DAF had little or no effect on EV70 replication. We also found that neither the human coxsackievirus-adenovirus receptor nor intercellular cell adhesion molecule 1, which mediate the entry of coxsackie B viruses and coxsackievirus A21, respectively, functions as a receptor for EV70. EV70 binding to all cell lines was sensitive to sialidase treatment and to inhibition of O glycosylation by benzyl N-acetyl-α-d-galactosaminide. Taken together, these results suggest that a sialylated molecule(s) other than DAF serves as a receptor for EV70 on permissive human leukocyte cell lines.

scholarly journals Caspase-3 and -7 mediate apoptosis of human Chang's conjunctival cells induced by enterovirus 70

Virology ◽  
2006 ◽  
Vol 347 (2) ◽  
pp. 307-322 ◽  
Author(s):  
Dequan Chen ◽  
Donald E. Texada ◽  
Chris Duggan ◽  
Youping Deng ◽  
Thomas B. Redens ◽  
...  
Keyword(s):  
Caspase 3 ◽  
Conjunctival Cells ◽  
Enterovirus 70
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