Xenogeneic Collagen Matrix Versus Connective Tissue Graft: Case Series of Various Gingival Recession Treatments

Objectives: The objective of this study was to determine and estimate the changing levels of matrix metalloproteinases 1 and 8 (MMP-1 and MMP-8) in GCF at consecutive stages of healing after root coverage procedure via modified coronally advanced tunnel (MCAT) combined with either sub-epithelial connective tissue graft (SCTG) or collagen matrix (CM) and also to relate those changes to clinical outcomes of both therapeutic approaches. Materials and methods: The study involved 20 patients with a total of 91 recessions. Those on one side of the mandible received MCAT plus CM while the contralateral ones MCAT plus SCTG. The evaluation of MMP-1 and MMP-8 concentrations in Gingival Crevicular Fluid (GCF) took place at baseline, then at 1, 2, and 4 weeks, and finally at 3 months after surgery. Elisa protocol was applied to determine the levels of MMP-1 and MMP-8 in GCF. Results: Three-month observation revealed statistically significant changes in MMP-1, MMP-8 and Sulcus Fluid Flow Rate (SFFR) values after implementation of both techniques. A correlation was found between a difference in MMP-1 concentrations and gain in Keratinized Tissue (KT) after SCTG and CM. MMP-8 levels and a Gingival Thickness (GT) gain observed after CM was also correlated. Conclusions: A type of augmentative material does appear to determine the dynamics of MMP-1 secretion.

Download Full-text

Autologous Connective Tissue Graft or Xenogenic Collagen Matrix with Coronally Advanced Flaps for Coverage of Multiple Adjacent Gingival Recession

Journal Of Clinical Periodontology ◽

10.1111/jcpe.13466 ◽

2021 ◽

Author(s):

Maurizio S. Tonetti ◽

Pierpaolo Cortellini ◽

Daniele Bonaccini ◽

Ke Deng ◽

Francesco Cairo ◽

...

Keyword(s):

Connective Tissue ◽

Collagen Matrix ◽

Gingival Recession ◽

Connective Tissue Graft ◽

Tissue Graft

Download Full-text

Palatal Harvesting Technique Modification for Better Control of the Connective Tissue Graft Dimensions

Brazilian Dental Journal ◽

10.1590/0103-6440201302343 ◽

2013 ◽

Vol 24 (6) ◽

pp. 565-568 ◽

Cited By ~ 1

Author(s):

Danilo Maeda Reino ◽

Arthur Belem Novaes Jr. ◽

Marcio Fernando de Moraes Grisi ◽

Luciana Prado Maia ◽

Sergio Luis Scombatti de Souza

Keyword(s):

Connective Tissue ◽

Donor Site ◽

Case Series ◽

Gingival Recession ◽

Connective Tissue Graft ◽

Tissue Graft ◽

Partial Thickness ◽

Harvesting Technique ◽

Subepithelial Connective Tissue Graft ◽

Graft Thickness

Subepithelial connective tissue graft (SCTG) has been extensively used for a variety of clinical applications. However, the surgical procedure may not allow control of graft thickness. The purpose of this case series is to illustrate a modification to the single incision palatal harvesting technique in order to control the SCTG thickness without increasing patient discomfort. Fifty cases from thirty systemically and periodontally healthy patients with at least one multiple gingival recession were treated with coronally advanced flaps combined with a SCTG. The palatal area served as the donor site, from where a single perpendicular incision was made to obtain a full thickness flap. Next, 1-2 mm of the flap was elevated and dissected to obtain a partial thickness flap. The graft remained attached to the full-partial thickness flap. After determining the desired SCTG thickness, the graft was harvested from the palatal flap. The patients healed uneventfully at 7 days postoperatively and primary closure was obtained for all palatal donor sites. The SCTG length and width varied depending on the needs of each case, but the SCTG thickness was well controlled with only 0.24 mm standard deviation. The suggested modification granted control of the SCTG dimensions and achieved complete wound closure within a week.

Download Full-text