An HMG-CoA Reductase Inhibitor, Cerivastatin, Suppresses Growth of Macrophages Expressing Matrix Metalloproteinases and Tissue Factor In Vivo and In Vitro

Pharmacological studies on NK-104, a novel potent HMG-CoA reductase inhibitor (1): Inhibitory effects on the enzyme (in vitro) and sterol synthesis (in vivo) in rats and hypolipidemic effects in dogs

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)46359-2 ◽

1995 ◽

Vol 67 ◽

pp. 99

Author(s):

Shunji Nakagwa ◽

Taro Aoki ◽

Hideo Suzuki ◽

Taro Tamaki ◽

Yasushi Wada ◽

...

Keyword(s):

Reductase Inhibitor ◽

Sterol Synthesis ◽

Inhibitory Effects ◽

Hmg Coa Reductase ◽

Pharmacological Studies ◽

In vitro and in vivo downregulation of the ATP binding cassette transporter B1 by the HMG-CoA reductase inhibitor simvastatin

Naunyn-Schmiedeberg s Archives of Pharmacology ◽

10.1007/s00210-015-1169-3 ◽

2015 ◽

Vol 389 (1) ◽

pp. 17-32 ◽

Cited By ~ 12

Author(s):

Bihter Atil ◽

Evelyn Berger-Sieczkowski ◽

Johanna Bardy ◽

Martin Werner ◽

Martin Hohenegger

Keyword(s):

Reductase Inhibitor ◽

Atp Binding ◽

Hmg Coa Reductase ◽

Atp Binding Cassette Transporter ◽

Coa Reductase ◽

Atp Binding Cassette

The HMG-CoA reductase inhibitor, atorvastatin, attenuates the effects of acute administration of amyloid-β1–42 in the rat hippocampus in vivo

Neuropharmacology ◽

10.1016/j.neuropharm.2006.07.031 ◽

2007 ◽

Vol 52 (1) ◽

pp. 136-145 ◽

Cited By ~ 50

Author(s):

Rachael M. Clarke ◽

Florence O'Connell ◽

Anthony Lyons ◽

Marina A. Lynch

Keyword(s):

Reductase Inhibitor ◽

Rat Hippocampus ◽

Acute Administration ◽

Hmg Coa Reductase ◽

The HMG-CoA reductase inhibitor simvastatin suppresses human testicular testosterone synthesis in vitro by a selective inhibitory effect on 17-ketosteroid-oxidoreductase enzyme activity

The Journal of Steroid Biochemistry and Molecular Biology ◽

10.1016/0960-0760(91)90333-z ◽

1991 ◽

Vol 38 (4) ◽

pp. 465-468 ◽

Cited By ~ 27

Author(s):

Anthony G.H. Smals ◽

Jos J.A.M. Weusten ◽

Theo J. Benraad

Keyword(s):

Enzyme Activity ◽

Reductase Inhibitor ◽

Inhibitory Effect ◽

Hmg Coa Reductase ◽

Coa Reductase ◽

Testosterone Synthesis

Pharmacological concentrations of the HMG-COA reductase inhibitor lovastatin decrease the formation of the Alzheimer beta -amyloid peptide em in vitro em and in patients

Frontiers in Bioscience ◽

10.2741/a739 ◽

2002 ◽

Vol 7 (1) ◽

pp. a50-59 ◽

Cited By ~ 1

Author(s):

Joseph D Buxbaum

Keyword(s):

Reductase Inhibitor ◽

Beta Amyloid ◽

Amyloid Peptide ◽

Hmg Coa Reductase ◽

Beta Amyloid Peptide ◽

HMG-CoA Reductase Inhibitor Protects Against In Vivo Arterial Thrombosis by Augmenting Platelet-Derived Nitric Oxide Release in Rats

Journal of Cardiovascular Pharmacology ◽

10.1097/01.fjc.0000157456.45691.d4 ◽

2005 ◽

Vol 45 (4) ◽

pp. 375-381 ◽

Cited By ~ 20

Author(s):

Shinji Yokoyama ◽

Hisao Ikeda ◽

Nobuya Haramaki ◽

Hideo Yasukawa ◽

Atsushi Katoh ◽

...

Keyword(s):

Nitric Oxide ◽

Arterial Thrombosis ◽

Reductase Inhibitor ◽

Hmg Coa Reductase ◽

Nitric Oxide Release ◽

Molecular rationale delineating the role of lycopene as a potent HMG-CoA reductase inhibitor: in vitro and in silico study

Natural Product Research ◽

10.1080/14786419.2015.1108977 ◽

2015 ◽

Vol 30 (18) ◽

pp. 2111-2114 ◽

Cited By ~ 17

Author(s):

Sahir Sultan Alvi ◽

Danish Iqbal ◽

Saheem Ahmad ◽

M. Salman Khan

Keyword(s):

In Silico ◽

Reductase Inhibitor ◽

Hmg Coa Reductase ◽

In Silico Study ◽

In vitro antitumor activity of cerivastatin, a novel and potent HMG-CoA reductase inhibitor

FEBS Letters ◽

10.1016/s0014-5793(01)02736-3 ◽

2001 ◽

Vol 503 (2-3) ◽

pp. 219-220 ◽

Cited By ~ 8

Author(s):

Wojciech Feleszko ◽

Izabela Mlynarczuk ◽

Dominika Nowis

Keyword(s):

Antitumor Activity ◽

Reductase Inhibitor ◽

Hmg Coa Reductase ◽

Simvastatin, a potent HMG-CoA Reductase Inhibitor, inhibits the Proliferation of Human and Bovine Endothelial Cells in vitro

Journal of Atherosclerosis and Thrombosis ◽

10.5551/jat1994.4.102 ◽

1998 ◽

Vol 4 (3) ◽

pp. 102-106 ◽

Cited By ~ 9

Author(s):

Ikuko Sato ◽

Lijuan Ma ◽

Masayuki Ikeda ◽

Ikuo Morita ◽

Sei-itsu Murota

Keyword(s):

Endothelial Cells ◽

Reductase Inhibitor ◽

Hmg Coa Reductase ◽

Bovine Endothelial Cells ◽

In vitro inhibition of simvastatin metabolism, a HMG-CoA reductase inhibitor in human and rat liver by bergamottin, a component of grapefruit juice

European Journal of Pharmaceutical Sciences ◽

10.1016/s0928-0987(02)00222-1 ◽

2003 ◽

Vol 18 (1) ◽

pp. 31-35 ◽

Cited By ~ 18

Author(s):

Nathalie Le Goff-Klein ◽

Jean-Claude Koffel ◽

Louis Jung ◽

Geneviève Ubeaud

Keyword(s):

Rat Liver ◽

Reductase Inhibitor ◽

Grapefruit Juice ◽

Hmg Coa Reductase ◽

In Vitro Inhibition ◽