scholarly journals Effect of age and spontaneous hypertension on the tachyphylaxis to 5-hydroxytryptamine and angiotensin II in the isolated rat kidney.

Hypertension ◽  
1981 ◽  
Vol 3 (6) ◽  
pp. 718-724 ◽  
Author(s):  
C De Mey ◽  
P M Vanhoutte
1982 ◽  
Vol 60 (10) ◽  
pp. 1311-1314 ◽  
Author(s):  
Thomas H. Steele ◽  
Jeanne H. Gottstein ◽  
Laura Challoner-Hue

We examined the action of angiotensin II (AII) on isolated rat kidney perfused with a recirculating cell-free solution at either 12 pKa (90 mmHg) or 17 kPa (128 mmHg). The renal perfusion pressure was maintained constant while sufficient All was added to increase the renal vascular resistance by 50%. In the low-pressure kidneys, AII increased the glomerular filtration rate (GFR) by 155%, increased sodium reabsorption by 157%, and decreased the urine sodium concentration by 34% without affecting sodium excretion. In the high-pressure kidneys, GFR initially was significantly greater but was not affected by AII. In these experiments, AII had no effect on sodium reabsorption or excretion and decreased the urine sodium concentration by 7%. The data suggest that AII could be involved in autoregulation of the GFR without producing large changes in sodium excretion.


Critical Care ◽  
10.1186/cc894 ◽  
2000 ◽  
Vol 4 (Suppl 1) ◽  
pp. P174
Author(s):  
M Heringlake ◽  
K Wagner ◽  
L Bahlmann ◽  
S Klaus ◽  
J Schumacher ◽  
...  

1991 ◽  
Vol 121 (1) ◽  
pp. 57-64 ◽  
Author(s):  
Delores M. Bowers-Komro ◽  
Donald B. McCormick

1975 ◽  
Vol 33 (1) ◽  
pp. 197-200 ◽  
Author(s):  
Robert Vandongen ◽  
Dianne M. Greenwood

1982 ◽  
Vol 4 ◽  
pp. S122-S124
Author(s):  
P. W. de Leeuw ◽  
P. L. Batenburg ◽  
W. H. Birkenhäger

2012 ◽  
Vol 1820 (12) ◽  
pp. 1940-1950 ◽  
Author(s):  
Fatemeh Shaki ◽  
Mir-Jamal Hosseini ◽  
Mahmoud Ghazi-Khansari ◽  
Jalal Pourahmad

1977 ◽  
Vol 26 (24) ◽  
pp. 2463-2468 ◽  
Author(s):  
Gregory J. Cooney ◽  
Anthony G. Dawson

1971 ◽  
Vol 156 (4) ◽  
pp. 268-282 ◽  
Author(s):  
H. Franke ◽  
H. Huland ◽  
Ch. Weiss ◽  
K. Unsicker

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