Discordance Between Coronary Flow Reserve and the Index of Microcirculatory Resistance Post-Revascularization for ST-Segment–Elevation Myocardial Infarction

2021 ◽  
Author(s):  
Klio Konstantinou ◽  
Thomas R. Keeble ◽  
John R. Davies ◽  
Reto A. Gamma ◽  
Kare H. Tang ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Coronary Flow Reserve ◽  
Coronary Flow ◽  
St Segment Elevation ◽  
Segment Elevation Myocardial Infarction ◽  
Flow Reserve ◽  
St Segment ◽  
Index Of Microcirculatory Resistance

scholarly journals Invasive Evaluation of the Microvasculature in Acute Myocardial Infarction: Coronary Flow Reserve versus the Index of Microcirculatory Resistance

2019 ◽  
Vol 9 (1) ◽  
pp. 86 ◽  
Author(s):  
John-Ross D. Clarke ◽  
Randol Kennedy ◽  
Freddy Duarte Lau ◽  
Gilead I. Lancaster ◽  
Stuart W. Zarich
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Coronary Flow Reserve ◽  
Coronary Flow ◽  
English Language ◽  
St Segment Elevation ◽  
Flow Reserve ◽  
Language Studies ◽  
Index Of Microcirculatory Resistance ◽  
Invasive Evaluation

Acute myocardial infarction (AMI) is one of the most common causes of death in both the developed and developing world. It has high associated morbidity despite prompt institution of recommended therapy. The focus over the last few decades in ST-segment elevation AMI has been on timely reperfusion of the epicardial vessel. However, microvascular consequences after reperfusion, such as microvascular obstruction (MVO), are equally reliable predictors of outcome. The attention on the microcirculation has meant that traditional angiographic/anatomic methods are insufficient. We searched PubMed and the Cochrane database for English-language studies published between January 2000 and November 2019 that investigated the use of invasive physiologic tools in AMI. Based on these results, we provide a comprehensive review regarding the role for the invasive evaluation of the microcirculation in AMI, with specific emphasis on coronary flow reserve (CFR) and the index of microcirculatory resistance (IMR).

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