Airway Responsiveness to Intravenous and Inhaled Acetylcholine in the Guinea Pig after Cigarette Smoke Exposure

1987 ◽  
Vol 136 (5) ◽  
pp. 1158-1162 ◽  
Author(s):  
Alan L. James ◽  
Peter Dirks ◽  
Hitoshi Ohtaka ◽  
R. Robert Schellenberg ◽  
James C. Hogg
Keyword(s):  
Guinea Pig ◽  
Cigarette Smoke ◽  
Airway Responsiveness ◽  
Smoke Exposure ◽  
Cigarette Smoke Exposure

scholarly journals Systemic effects of cigarette smoke exposure in the guinea pig

2006 ◽  
Vol 100 (7) ◽  
pp. 1186-1194 ◽  
Author(s):  
Esther Ardite ◽  
Víctor I. Peinado ◽  
Roberto A. Rabinovich ◽  
José C. Fernández-Checa ◽  
Josep Roca ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Cigarette Smoke ◽  
Smoke Exposure ◽  
Cigarette Smoke Exposure ◽  
Systemic Effects

Long Term Cigarette Smoke Exposure Does Not Increase Airway Responsiveness in Rats

Lung ◽  
1998 ◽  
Vol 176 (4) ◽  
pp. 289-297 ◽  
Author(s):  
J. L. Wright ◽  
J.-P. Sun ◽  
S. Vedal
Keyword(s):  
Cigarette Smoke ◽  
Airway Responsiveness ◽  
Smoke Exposure ◽  
Cigarette Smoke Exposure

Effect of urethan anesthesia on cigarette smoke-induced airway injury in guinea pigs

1987 ◽  
Vol 63 (1) ◽  
pp. 84-91 ◽  
Author(s):  
A. R. Burns ◽  
J. Van Oostdam ◽  
D. C. Walker ◽  
J. C. Hogg
Keyword(s):  
Guinea Pig ◽  
Cigarette Smoke ◽  
Airway Resistance ◽  
Fluorescein Isothiocyanate ◽  
Airway Responsiveness ◽  
Smoke Exposure ◽  
Airway Reactivity ◽  
Mucosal Permeability ◽  
Airway Injury ◽  
Fluorescein Isothiocyanate Dextran

The effect of urethan anesthesia on cigarette smoke-induced airway responsiveness and permeability was studied in the guinea pig. Airway responsiveness was determined by measuring changes to airway resistance to graded doses of aerosolized histamine, and mucosal permeability was determined by measuring the appearance of fluorescein isothiocyanate-dextran (FITC-D) in the blood and examining its distribution in lung tissue after it had been delivered to the lung in an aerosol. The results confirm previous studies that smoke exposure increased airway responsiveness and mucosal permeability. They also show that urethan anesthesia administered before smoke exposure prevented the smoke-related changes in airway reactivity and mucosal permeability. In animals that remained conscious during the smoke exposure, there was increased deposition of the dextran in the regions of the bronchioloalveolar junctions with a more rapid uptake of FITC-D into the blood. We postulate that, when urethan anesthesia is administered before smoke exposure, the exudative phase of the inflammatory reaction produced by smoke exposure is suppressed.

The effect of mainstream and sidestream cigarette smoke exposure on oxygen defense mechanisms of guinea pig erythrocytes

1993 ◽  
Vol 8 (3) ◽  
pp. 119-125 ◽  
Author(s):  
Shyamali Mukherjee ◽  
Letha Woods ◽  
Zada Weston ◽  
Arthur B. Williams ◽  
Salil K. Das
Keyword(s):  
Guinea Pig ◽  
Cigarette Smoke ◽  
Defense Mechanisms ◽  
Smoke Exposure ◽  
Cigarette Smoke Exposure

Effects of four antitussives on airway neurogenic inflammation in a guinea pig model of chronic cough induced by cigarette smoke exposure

2013 ◽  
Vol 62 (12) ◽  
pp. 1053-1061 ◽  
Author(s):  
Yu-long Luo ◽  
Pei-bo Li ◽  
Chen-chen Zhang ◽  
Yan-fang Zheng ◽  
Sheng Wang ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Cigarette Smoke ◽  
Chronic Cough ◽  
Neurogenic Inflammation ◽  
Smoke Exposure ◽  
Pig Model ◽  
Cigarette Smoke Exposure ◽  
Guinea Pig Model

Mainstream and sidestream cigarette smoke exposure increases retinol in guinea pig lungs

1995 ◽  
Vol 18 (3) ◽  
pp. 507-514 ◽  
Author(s):  
Shyamali Mukherjee ◽  
Tultul Nayyar ◽  
Frank Chytil ◽  
Salil K. Das
Keyword(s):  
Guinea Pig ◽  
Cigarette Smoke ◽  
Smoke Exposure ◽  
Cigarette Smoke Exposure
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