scholarly journals Evaluation of Time Domain and Spectral Domain Optical Coherence Tomography in the Measurement of Diabetic Macular Edema

2008 ◽  
Vol 49 (10) ◽  
pp. 4290 ◽  
Author(s):  
Farzin Forooghian ◽  
Catherine Cukras ◽  
Catherine B. Meyerle ◽  
Emily Y. Chew ◽  
Wai T. Wong
2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Masashi Kakinoki ◽  
Taichirou Miyake ◽  
Osamu Sawada ◽  
Tomoko Sawada ◽  
Hajime Kawamura ◽  
...  

Purpose. To compare the macular thicknesses in diabetic macular edema (DME) measured with spectral-domain optical coherence tomography (SD-OCT) and time-domain (TD) OCT.Patients and Methods.The average macular thicknesses of 50 eyes of 29 patients with DME were measured using SD-OCT and TD-OCT.Results.The mean macular thicknesses measured with TD-OCT and SD-OCT were401.5±117.8 μm (mean ± SD) and446.2±123.5 μm, respectively. The macular thicknesses measured with the two devices were well correlated (Pearson's product moment correlation,r=0.977,P<0.001). A significant correlation was found between the best-corrected visual acuity and the retinal thickness measured by TD-OCT and SD-OCT (Pearson's product moment correlation, TD-OCT,r=0.34;P<0.05; SD-OCT,r=0.32;P<0.05).Discussion.The mean macular thickness measured with SD-OCT was about 45 μm thicker than that measured with TD-OCT. Attention should be paid when comparing data obtained using different OCT machines.


Author(s):  
Sandeep Saxena ◽  
Levent Akduman ◽  
Carsten H. Meyer

AbstractAdvances in spectral-domain optical coherence tomography (SD-OCT) technology have enhanced the understanding of external limiting membrane (ELM) and ellipsoid zone (EZ) in diabetic macular edema. An increase in VEGF has been demonstrated to be associated with sequential ELM and EZ disruption on SD-OCT. An intact ELM is a prerequisite for an intact EZ in DME. Anti-VEGF therapy leads to restoration of barrier effect of ELM. The ELM restores first followed by EZ restoration.


2009 ◽  
Vol 40 (6) ◽  
pp. 548-553 ◽  
Author(s):  
Jean-Antoine C. Pournaras ◽  
Ali Erginay ◽  
Zineb Lazrak ◽  
Alain Gaudric ◽  
Pascale Massin

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