scholarly journals Comparison of Macular Thickness in Diabetic Macular Edema Using Spectral-Domain Optical Coherence Tomography and Time-Domain Optical Coherence Tomography

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Masashi Kakinoki ◽  
Taichirou Miyake ◽  
Osamu Sawada ◽  
Tomoko Sawada ◽  
Hajime Kawamura ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Time Domain ◽  
Macular Thickness ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Corrected Visual Acuity ◽  
The Mean ◽  
Sd Oct

Purpose. To compare the macular thicknesses in diabetic macular edema (DME) measured with spectral-domain optical coherence tomography (SD-OCT) and time-domain (TD) OCT.Patients and Methods.The average macular thicknesses of 50 eyes of 29 patients with DME were measured using SD-OCT and TD-OCT.Results.The mean macular thicknesses measured with TD-OCT and SD-OCT were401.5±117.8 μm (mean ± SD) and446.2±123.5 μm, respectively. The macular thicknesses measured with the two devices were well correlated (Pearson's product moment correlation,r=0.977,P<0.001). A significant correlation was found between the best-corrected visual acuity and the retinal thickness measured by TD-OCT and SD-OCT (Pearson's product moment correlation, TD-OCT,r=0.34;P<0.05; SD-OCT,r=0.32;P<0.05).Discussion.The mean macular thickness measured with SD-OCT was about 45 μm thicker than that measured with TD-OCT. Attention should be paid when comparing data obtained using different OCT machines.

scholarly journals External limiting membrane: retinal structural barrier in diabetic macular edema

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Sandeep Saxena ◽  
Levent Akduman ◽  
Carsten H. Meyer
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Barrier Effect ◽  
External Limiting Membrane ◽  
Ellipsoid Zone ◽  
Structural Barrier ◽  
Sd Oct

AbstractAdvances in spectral-domain optical coherence tomography (SD-OCT) technology have enhanced the understanding of external limiting membrane (ELM) and ellipsoid zone (EZ) in diabetic macular edema. An increase in VEGF has been demonstrated to be associated with sequential ELM and EZ disruption on SD-OCT. An intact ELM is a prerequisite for an intact EZ in DME. Anti-VEGF therapy leads to restoration of barrier effect of ELM. The ELM restores first followed by EZ restoration.

scholarly journals Evaluation of Time Domain and Spectral Domain Optical Coherence Tomography in the Measurement of Diabetic Macular Edema

2008 ◽  
Vol 49 (10) ◽  
pp. 4290 ◽  
Author(s):  
Farzin Forooghian ◽  
Catherine Cukras ◽  
Catherine B. Meyerle ◽  
Emily Y. Chew ◽  
Wai T. Wong
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Time Domain ◽  
Spectral Domain ◽  
Optical Coherence

scholarly journals Comparison of Time Domain and Spectral Domain Optical Coherence Tomography in Measurement of Macular Thickness in Macular Edema Secondary to Diabetic Retinopathy and Retinal Vein Occlusion

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Elham Hatef ◽  
Afsheen Khwaja ◽  
Zubir Rentiya ◽  
Mohamed Ibrahim ◽  
Matthew Shulman ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Diabetic Retinopathy ◽  
Macular Edema ◽  
Time Domain ◽  
Macular Thickness ◽  
Spectral Domain ◽  
Vein Occlusion ◽  
Spectralis Oct ◽  
Stratus Oct ◽  
Sd Oct

Purpose. To evaluate macular thickness, agreement, and intraclass repeatability in three optical coherence tomography (OCT) devices: the time domain (TD) Stratus OCT and two spectral domain (SD) OCTs, Spectralis and Cirrus SD-OCT, in eyes with macular edema secondary to diabetic retinopathy (DR) and retinal vein occlusion (VO).Methods. In a prospective observational study at a university-based retina practice, retinal thickness tomography was performed simultaneously for fifty-eight patients (91 eyes) with DR and VO employing a time domain and two spectral domain OCTs. Agreement in macular measurements was assessed by constructing Bland-Altman plots. Intraclass repeatability was assessed by intraclass correlation coefficients (ICCs).Results. Based on the Bland-Altman plots for central macular thickness, there was low agreement between the measurements of Cirrus SD-OCT and Stratus OCT, Spectralis OCT and Stratus OCT, as well as Spectralis OCT and Cirrus SD-OCT among DR and RVO patients. All three devices demonstrated high intraclass repeatability, with ICC of 98% for Stratus OCT, 97% for Cirrus SD-OCT, and 100% for Spectralis OCT among DR patients. The ICC was 97% for Stratus OCT, 79% for Cirrus SD-OCT, and 91% for Spectralis OCT among RVO patients.Conclusion. There are low agreements among interdevice measurements. However, intraclass repeatability is high in both TD and SD-OCT devices.

Spectral Domain Optical Coherence Tomography in Diabetic Macular Edema

2009 ◽  
Vol 40 (6) ◽  
pp. 548-553 ◽  
Author(s):  
Jean-Antoine C. Pournaras ◽  
Ali Erginay ◽  
Zineb Lazrak ◽  
Alain Gaudric ◽  
Pascale Massin
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Spectral Domain ◽  
Optical Coherence

scholarly journals Macular thickness measurements of healthy, naïve cynomolgus monkeys assessed with spectral-domain optical coherence tomography (SD-OCT)

PLoS ONE ◽  
2019 ◽  
Vol 14 (10) ◽  
pp. e0222850 ◽  
Author(s):  
Nora Denk ◽  
Peter Maloca ◽  
Guido Steiner ◽  
Christian Freichel ◽  
Simon Bassett ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Thickness ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Cynomolgus Monkeys ◽  
Thickness Measurements ◽  
Sd Oct
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