Retinoblastoma (RB) is the most common ocular malignant neoplasm of childhood. Bilateral or unilateral intraocular RB in conjunction with a primitive neuroectodermal tumor (PNET) of the pineal region (i.e. pineoblastoma) is termed as trilateral retinoblastoma (TRB). Retinoblastoma may spread along the optic nerve to the intracranial compartment to give drop metastases in the subarachnoid space or it can spread through hematogenous and lymphatic routes. Phthisis bulbi (PB) is a relatively uncommon presentation of retinoblastoma. We report a case of trilateral retinoblastoma with phthisical left eye and extensive leptomeningeal metastasis in a 3-year-old female child.DOI: http://dx.doi.org/10.3126/njr.v3i2.9621 Nepalese Journal of Radiology Vol.3(2)July-Dec, 2013: 92-96
Author Response: Posture-Dependent Collapse of the Optic Nerve Subarachnoid Space: A Combined MRI and Modeling Study
