Efficacy and Safety of Extended-Release Venlafaxine in the Treatment of Generalized Anxiety Disorder in Children and Adolescents: Two Placebo-Controlled Trials

2007 ◽  
Vol 164 (2) ◽  
pp. 290-300 ◽  
Author(s):  
Moira A. Rynn ◽  
Mark A. Riddle ◽  
Paul P. Yeung ◽  
Nadia R. Kunz
Keyword(s):  
Anxiety Disorder ◽  
Children And Adolescents ◽  
Generalized Anxiety Disorder ◽  
Extended Release ◽  
Generalized Anxiety ◽  
Controlled Trials ◽  
Efficacy And Safety

scholarly journals Digital Interventions for Generalized Anxiety Disorder (GAD): Systematic Review and Network Meta-Analysis

2021 ◽  
Vol 12 ◽  
Author(s):  
Pedro Saramago ◽  
Lina Gega ◽  
David Marshall ◽  
Georgios F. Nikolaidis ◽  
Dina Jankovic ◽  
...  
Keyword(s):  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Meta Analysis ◽  
Antidepressant Medication ◽  
Generalized Anxiety ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Self Help ◽  
Digital Interventions ◽  
Better Than

Background: Generalized anxiety disorder is the most common mental health condition based on weekly prevalence. Digital interventions have been used as alternatives or as supplements to conventional therapies to improve access, patient choice, and clinical outcomes. Little is known about their comparative effectiveness for generalized anxiety disorder.Methods: We conducted a systematic review and network meta-analysis of randomized controlled trials comparing digital interventions with medication, non-digital interventions, non-therapeutic controls, and no intervention.Results: We included 21 randomized controlled trials with a total of 2,350 participants from generalized anxiety disorder populations. Pooled outcomes using analysis of Covariance and rankograms based on the surface under the cumulative ranking curves indicated that antidepressant medication and group therapy had a higher probability than digital interventions of being the “best” intervention. Supported digital interventions were not necessarily “better” than unsupported (pure self-help) ones.Conclusions: Due to very wide confidence intervals, network meta-analysis results were inconclusive as to whether digital interventions are better than no intervention and non-therapeutic active controls, or whether they confer an additional benefit to standard therapy. Future research needs to compare digital interventions with one-to-one therapy and with manualized non-digital self-help and to include antidepressant medication as a treatment comparator and effect modifier.

Efficacy and Safety of Vilazodone in Patients With Generalized Anxiety Disorder

2016 ◽  
Vol 77 (12) ◽  
pp. 1687-1694 ◽  
Author(s):  
Suresh Durgam ◽  
Carl Gommoll ◽  
Giovanna Forero ◽  
Rene Nunez ◽  
Xiongwen Tang ◽  
...  
Keyword(s):  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Generalized Anxiety ◽  
Efficacy And Safety

Efficacy and Safety of Pregabalin in the Treatment of Generalized Anxiety Disorder

2006 ◽  
Vol 67 (05) ◽  
pp. 771-782 ◽  
Author(s):  
Stuart A. Montgomery ◽  
Kathy Tobias ◽  
Gwen L. Zornberg ◽  
Siegfried Kasper ◽  
Atul C. Pande
Keyword(s):  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Generalized Anxiety ◽  
Efficacy And Safety

scholarly journals Efficacy of Venlafaxine Extended-Release Capsules in Nondepressed Outpatients With Generalized Anxiety Disorder

JAMA ◽  
2000 ◽  
Vol 283 (23) ◽  
pp. 3082 ◽  
Author(s):  
Alan J. Gelenberg ◽  
R. Bruce Lydiard ◽  
Richard L. Rudolph ◽  
Loren Aguiar ◽  
J. Thomas Haskins ◽  
...  
Keyword(s):  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Extended Release ◽  
Generalized Anxiety
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