scholarly journals A fatal outcome in a patient with coeliac disease who suspended a strict gluten-free diet: a case report

2021 ◽  
Vol 49 (12) ◽  
pp. 030006052110610
Author(s):  
Chong Lu ◽  
Xiao-Juan Zheng ◽  
Hong-Jun Hua ◽  
Qun-Ying Wang

Coeliac disease (CD) is an autoimmune small bowel disease that occurs in susceptible individuals that develop an immunological reaction to gluten. A strict gluten-free diet (GFD) is the primary treatment for CD. This case report describes a patient with CD recurrence due to a discontinuation of a strict GFD by the patient. After recurrence, the patient developed fever and pancytopaenia, and quickly died of haemophagocytic lymphohistiocytosis (HLH). To the best of our knowledge, this is the first description of a case of CD associated with HLH due to discontinued GFD, which may contribute to improving the awareness of the importance of maintaining a strict GFD and having regular follow-up examinations.

2020 ◽  
Vol 2 (3) ◽  
pp. 318-326
Author(s):  
Humayun Muhammad ◽  
Sue Reeves ◽  
Sauid Ishaq ◽  
Yvonne Jeanes

Coeliac disease is a chronic inflammatory disorder of the small bowel, characterised by permanent intolerance to gluten. The only current and effective treatment for coeliac disease is a gluten free diet [GFD], however this is challenging for patients to adhere to. The review aims to identify published interventions designed to improve patients’ adherence to a GFD. Ten intervention studies were identified and included within the review; whilst heterogeneous in delivery, all included an educational, behavioural, and practical element. Five interventions significantly improved dietary adherence, these included follow-up appointments, a telephone clinic, an online course, cooking sessions and psychological support. All studies were small and used varied methods to assess adherence. There is a paucity of well-designed interventions to promote dietary adherence, in future more robust methods for ascertaining adherence is needed, we recommend greater inclusion of dietetic assessment and combining more than one method for assessing adherence.


Author(s):  
R. Mark Beattie ◽  
Anil Dhawan ◽  
John W.L. Puntis

Gluten Challenge 244Advice from the dietitan 245Monitoring 247A gluten-free diet is the primary treatment for coeliac disease. This involves the complete exclusion of wheat, rye, oats, and barley, although the toxicity of oats is still in question. If properly treated, patients should be able to lead a normal, active life....


2009 ◽  
Vol 68 (3) ◽  
pp. 249-251 ◽  
Author(s):  
Claire Stuckey ◽  
Jacqui Lowdon ◽  
Peter Howdle

It seems obvious to healthcare professionals that patients with coeliac disease should receive regular follow-up. Surprisingly, there is little evidence that patients benefit in terms of reduced morbidity or mortality. However, several authoritative bodies have published guidelines on the management of coeliac disease that recommend regular follow-up. There is good evidence that compliance with a gluten-free diet reduces the risk of complications such as osteoporosis or small bowel lymphoma. Compliance is enhanced particularly by education about the disease and the gluten-free diet and by support from peers or professionals. Such input can be provided by regular follow-up, which thereby should improve compliance and hence long-term health. The consensus of the recommendations for follow-up suggests an annual review by a physician and dietitian. At annual follow-up the disease status can be checked and nutritional advice can be given, including checking the adequacy of, and the compliance with, the gluten-free diet. Complications and associated medical conditions can be sought, genetic risks explained and support and reassurance given. Specialist dietitians have particular expertise in relation to diet and nutritional management; specialist clinicians have a broader range of expertise in many aspects of management of the disease. A team approach for providing follow-up is the ideal, with a clinician and dietitian, both with expertise in coeliac disease, being involved. No one particular group of healthcare professionals is necessarily better than the other at providing follow-up.


2014 ◽  
Vol 40 (6) ◽  
pp. 639-647 ◽  
Author(s):  
G. Galli ◽  
G. Esposito ◽  
E. Lahner ◽  
E. Pilozzi ◽  
V. D. Corleto ◽  
...  

2005 ◽  
Vol 5 (1) ◽  
Author(s):  
Päivi A Pynnönen ◽  
Erkki T Isometsä ◽  
Matti A Verkasalo ◽  
Seppo A Kähkönen ◽  
Ilkka Sipilä ◽  
...  

2021 ◽  
Vol 2021 (4) ◽  
Author(s):  
Leen Jamel Doya ◽  
Naya Talal Hassan ◽  
Narmin Hajo ◽  
Fareeda Wasfy Bijow ◽  
Alexander Ibrahim ◽  
...  

ABSTRACT Coeliac disease (CD) and cystic fibrosis (CF) are well known as the most common causes of chronic intestinal malabsorption in childhood. The coexistence of coeliac disease with cystic fibrosis is uncommon. Here, we describe the case of cystic fibrosis in a patient diagnosed with coeliac disease who failed to respond clinically to a gluten-free diet and had persistent steatorrhea and failure to thrive.


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