Do Selective COX-2 Inhibitors Affect Pain Control and Healing After Arthroscopic Rotator Cuff Repair? Response

2018 ◽  
Vol 46 (6) ◽  
pp. NP26-NP27
Author(s):  
Joo Han Oh ◽  
Hyuk Jun Seo ◽  
Ye-Hyun Lee ◽  
Hye-Yeon Choi ◽  
Ho Yun Joung ◽  
...  
2017 ◽  
Vol 46 (3) ◽  
pp. 679-686 ◽  
Author(s):  
Joo Han Oh ◽  
Hyuk Jun Seo ◽  
Ye-Hyun Lee ◽  
Hye-Yeon Choi ◽  
Ho Yun Joung ◽  
...  

Background: Selective cyclooxygenase (COX)–2 inhibitors are commonly used analgesics that provide similar analgesia as that of other analgesics but with fewer adverse effects. However, few prospective studies have performed comparative analyses in this regard. Purpose: To evaluate the efficacy of a selective COX-2 inhibitor in early postoperative pain control, satisfaction with pain management, and incidence of systemic adverse effects in patients undergoing arthroscopic rotator cuff repair. Study Design: Randomized controlled trial; Level of evidence, 1. Methods: This study included 180 patients who underwent arthroscopic rotator cuff repair between September 2011 and August 2012. The patients were randomly assigned to receive celecoxib, ibuprofen, or tramadol (n = 60 each). Visual analog scale (VAS) scores for pain intensity and satisfaction with medication, incidence of adverse effects, and use of rescue medication were recorded and compared between the 3 groups at 3 days and 2 weeks after surgery. Magnetic resonance and ultrasonography images of 82 patients were retrospectively reviewed at least 24 months after surgery, along with the range of motion and pain VAS and functional scores. Results: There were no significant differences among the 3 groups in terms of pain intensity, incidence of adverse effects, or dosage of rescue medication at 3 days or 2 weeks after surgery. Pain VAS and functional scores at the final follow-up were also comparable among the 3 groups. However, the retear rate in the celecoxib group (11/30 [37%]) was significantly higher than those in the ibuprofen (2/27 [7%]) and tramadol (1/25 [4%]) groups ( P = .009). Conclusion: Despite having similar postoperative analgesic effects as other nonsteroidal anti-inflammatory drugs and opioids, selective COX-2 inhibitors should not be used for postoperative analgesia because they might negatively affect tendon-to-bone healing after surgical repair. Registration: NCT02850211 ( ClinicalTrials.gov identifier)


2019 ◽  
Vol 11 (2) ◽  
pp. 192 ◽  
Author(s):  
Hisahiro Tonotsuka ◽  
Hiroyuki Sugaya ◽  
Norimasa Takahashi ◽  
Nobuaki Kawai ◽  
Hajime Sugiyama ◽  
...  

2016 ◽  
Vol 25 (7) ◽  
pp. 1204-1213 ◽  
Author(s):  
Carlos A. Uquillas ◽  
Brian M. Capogna ◽  
William H. Rossy ◽  
Siddharth A. Mahure ◽  
Andrew S. Rokito

2012 ◽  
Vol 15 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Chang Min Park ◽  
Jong Hae Kim ◽  
Suk Jun Kim ◽  
Chang Hyuk Choi

PURPOSE: The purpose of this study was to identify the effectiveness of multimodal pain control method in an early phase after arthroscopic rotator cuff repair, under interscalene brachial plexus block, this study was performed.MATERIALS AND METHODS: The study was progressed with the 80 cases of arthroscopic rotator cuff repair. Interscalene brachial plexus block was used to all of the 80 cases and patients were divided into 2 groups. Group A consisted of patients injected with bupivacaine, through subacromial space catheter after surgery, and group B consisted of patients with additional method of multimodal pain control using oral opioids, acetaminophen-tramadol complex and selective COX2 inhibitor. Subacromial cathter was removed after injection in both groups. The pain during the day time and night time was compared on the operation day, postoperative 1st, 2nd, 3rd day and 2nd weeks, and it was measured with VAS (visual analogue scale) score. Additionally, the number of ketolorac injection and side-effect related to analgesics was compared between the 2 groups.RESULTS: The mean VAS score of night time on the operation day and day/night time pain of the 1st, 2nd, 3rd day and 2nd weeks was 7.4, 7.0/6.8, 4.5/5.2, 4.8/5.0, 2.2/2.7 on group A and 6.5, 4.3/5.4, 3.2/4.3, 3.0/4.1, 2.4/2.5 on group B, respectively. Significant difference was observed in the night pain on the operation day, 1st, 2nd, 3rd day time and 1st night time pain (p<.05). The average number of ketololac injection was 1.1 and 0.5 in each group, and there was no difference in the frequency of side effects.CONCLUSION: Multimodal pain control method, after arthroscopic rotator cuff repair, showed an effective early pain control and improved patients' satisfaction.


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