Warm antibody hemolytic anemia—a rare presentation of neonatal lupus

Lupus ◽  
2016 ◽  
Vol 26 (6) ◽  
pp. 661-663 ◽  
Author(s):  
Rohan Halder ◽  
Richa Malik ◽  
Rajesh Kashyap
Keyword(s):  
Hemolytic Anemia ◽  
Transient Response ◽  
Lupus Erythematosus ◽  
Neonatal Lupus ◽  
Rare Presentation ◽  
Neonatal Lupus Erythematosus ◽  
Cyclosporin Therapy ◽  
Pregnant Females ◽  
Steroid Refractory

Neonatal lupus erythematosus (NLE) affects 1%–2% pregnant females with autoimmunity. An infant presented with steroid refractory hemolytic anemia as a manifestation of NLE. A trial of withholding breastfeeding had a transient response, but infant was eventually put on cyclosporin therapy to control the hemolysis. Now he is thriving well and transfusion free.

Cytomegalovirus-Associated Hemolytic Anemia in an Infant Born to a Mother with Lupus

Neonatology ◽  
2021 ◽  
pp. 1-5
Author(s):  
Shunsuke Yamamoto ◽  
Akira Shiraishi ◽  
Masataka Ishimura ◽  
Yoshitomo Motomura ◽  
Yutaro Yada ◽  
...  
Keyword(s):  
Intensive Care ◽  
Hemolytic Anemia ◽  
Lupus Erythematosus ◽  
Pediatric Intensive Care ◽  
Igg Antibodies ◽  
Cmv Infection ◽  
Neonatal Lupus ◽  
Neonatal Lupus Erythematosus ◽  
Immune Hemolytic Anemia ◽  
Antiglobulin Test

A 31-day-old infant was admitted to the pediatric intensive care unit due to shock and anemia. The mother had systemic lupus erythematosus and direct antiglobulin test (DAT)-positive hemolytic anemia. The perinatal course of this infant and the mother was uneventful. Regular health check screenings revealed that activity, growth, and development were unremarkable at birth, 5, and 28 days of life. Passive immune hemolytic anemia due to neonatal lupus erythematosus was diagnosed based on a positive DAT for warm-type IgG antibodies, reticulocytosis, and lupus-specific antibodies at rehospitalization. It was complicated by cytomegalovirus (CMV) antigenemia. Umbilical cord blood and peripheral blood samples obtained from the infant at 5 days after birth were negative for CMV DNA. The infant was curatively treated by intensive care with repeated blood transfusions and antiviral therapy. This is the first report indicating that CMV infection exacerbates hemolytic anemia in patients with maternal red blood cell alloantibodies.

scholarly journals Synchronous skin lesions in mother and baby with neonatal lupus erythematosus

2021 ◽  
Author(s):  
Adrian Y. S. Lee ◽  
Alvin H. K. Tan ◽  
Catriona Brennan ◽  
Dimitra Beroukas ◽  
Tom P. Gordon ◽  
...  
Keyword(s):  
Lupus Erythematosus ◽  
Skin Lesions ◽  
Neonatal Lupus ◽  
Neonatal Lupus Erythematosus

Neonatal lupus erythematosus

1994 ◽  
Vol 19 (5) ◽  
pp. 409-411 ◽  
Author(s):  
R.E. JENKINS ◽  
A.R. KURWA ◽  
D.J. ATHERTON ◽  
M.M. BLACK
Keyword(s):  
Lupus Erythematosus ◽  
Neonatal Lupus ◽  
Neonatal Lupus Erythematosus

Neonatal lupus erythematosus syndrome

1991 ◽  
Vol 18 (5) ◽  
pp. 333-338 ◽  
Author(s):  
B. Maynard ◽  
K. M. Leiferman ◽  
M.S. Peters
Keyword(s):  
Lupus Erythematosus ◽  
Neonatal Lupus ◽  
Neonatal Lupus Erythematosus

Cutaneous telangiectases in neonatal lupus erythematosus

1995 ◽  
Vol 33 (1) ◽  
pp. 19-25 ◽  
Author(s):  
Caroline M Thornton ◽  
Lawrence F Eichenfield ◽  
Elizabeth A Shinall ◽  
Elaine Siegfried ◽  
Linda G Rabinowitz ◽  
...  
Keyword(s):  
Lupus Erythematosus ◽  
Neonatal Lupus ◽  
Neonatal Lupus Erythematosus
Sign in / Sign up

Export Citation Format

Share Document