Neonatal Lupus Erythematosus with Multisystem Organ Involvement Preceding Cutaneous Lesions

Lupus ◽  
1991 ◽  
Vol 1 (1) ◽  
pp. 49-50 ◽  
Author(s):  
Eduardo Fonseca ◽  
Félix Contreras ◽  
Enrique García-Frías ◽  
M. Carmen Carrascosa
Keyword(s):  
Lupus Erythematosus ◽  
Organ Involvement ◽  
Neonatal Lupus ◽  
Cutaneous Lesions ◽  
Neonatal Lupus Erythematosus

scholarly journals Congenital and neonatal lupus erythematosus: two case reports

2012 ◽  
Vol 87 (4) ◽  
pp. 625-628
Author(s):  
Marcos Noronha Frey ◽  
Ana Elisa Empinotti Ioppi ◽  
Gabriela Czarnobay Garbin ◽  
Roque Domingos Furian ◽  
Ana Elisa Kiszewski Bau
Keyword(s):  
Lupus Erythematosus ◽  
Antinuclear Antibodies ◽  
Case Reports ◽  
Nuclear Antigen ◽  
Neonatal Lupus ◽  
Cutaneous Lesions ◽  
Neonatal Lupus Erythematosus ◽  
Extractable Nuclear Antigen ◽  
The Moment ◽  
Congenital Variant

Neonatal lupus erythematosus is an autoimmune disease produced by the passage of maternal antinuclear antibodies and extractable nuclear antigen antibodies through the placenta. At the moment of the diagnosis, the mothers are asymptomatic in 40 to 60% of cases. The most common manifestations are cutaneous lesions and congenital heart block. The cutaneous findings are variable and usually begin within the first weeks or months of life. Congenital lupus erythematosus is a congenital variant of neonatal lupus erythematosus. We present one case of congenital lupus erythematosus and one case of neonatal lupus erythematous, showing the variability of this disease.

Neonatal lupus erythematosus presenting with rash, thrombocytopenia compounded by cytomegalovirus colonisation: a diagnostic dilemma

2020 ◽  
Vol 13 (6) ◽  
pp. e233873
Author(s):  
Gopal Agrawal ◽  
Bincy Varghese ◽  
Manish Balde ◽  
Sanjay Wazir
Keyword(s):  
Lupus Erythematosus ◽  
Organ Damage ◽  
Skin Lesions ◽  
Maternal Serum ◽  
Cmv Infection ◽  
Neonatal Lupus ◽  
Cutaneous Lesions ◽  
Diagnostic Dilemma ◽  
Neonatal Lupus Erythematosus ◽  
Erythematous Skin

Neonatal lupus erythematosus (NLE) should be considered when a newborn develops atrioventricular heart block along with the presence of autoantibodies to Sjogren’s syndrome autoantigens in the maternal serum. NLE can also present with features such as cutaneous lesions, hepatic dysfunction or haematological abnormalities. Differential diagnosis usually includes congenital infections as there is a significant overlap of symptoms with NLE. We report a case of NLE who had multiorgan involvement with macular erythematous skin lesions present at birth, and on investigation was found to have cytomegalovirus (CMV) infection. The diagnostic dilemma was whether to consider this infection as symptomatic or just colonisation. In the infant described, the absence of end organ damage specific to CMV infection (hearing loss, intracranial calcifications, retinitis, brain involvement) made a diagnosis of symptomatic CMV unlikely.

scholarly journals Synchronous skin lesions in mother and baby with neonatal lupus erythematosus

2021 ◽  
Author(s):  
Adrian Y. S. Lee ◽  
Alvin H. K. Tan ◽  
Catriona Brennan ◽  
Dimitra Beroukas ◽  
Tom P. Gordon ◽  
...  
Keyword(s):  
Lupus Erythematosus ◽  
Skin Lesions ◽  
Neonatal Lupus ◽  
Neonatal Lupus Erythematosus

Neonatal lupus erythematosus

1994 ◽  
Vol 19 (5) ◽  
pp. 409-411 ◽  
Author(s):  
R.E. JENKINS ◽  
A.R. KURWA ◽  
D.J. ATHERTON ◽  
M.M. BLACK
Keyword(s):  
Lupus Erythematosus ◽  
Neonatal Lupus ◽  
Neonatal Lupus Erythematosus

Neonatal lupus erythematosus syndrome

1991 ◽  
Vol 18 (5) ◽  
pp. 333-338 ◽  
Author(s):  
B. Maynard ◽  
K. M. Leiferman ◽  
M.S. Peters
Keyword(s):  
Lupus Erythematosus ◽  
Neonatal Lupus ◽  
Neonatal Lupus Erythematosus
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