Cardiac Dysrhythmias and Autonomic Dysfunction in Chronic Spinal Cord Injury: A 24-Hour Holter Monitoring and Heart Rate Variability Study

1999 ◽  
Vol 13 (4) ◽  
pp. 235-241 ◽  
Author(s):  
Gülçin Demirel ◽  
Seref Demirel ◽  
Hürriyet Yilmaz ◽  
Vakur Akkaya ◽  
Dursun Atilgan ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Heart Rate ◽  
Spinal Cord Injury ◽  
Heart Rate Variability ◽  
Frequency Domain ◽  
Autonomic Dysfunction ◽  
Time Domain ◽  
Chronic Spinal Cord Injury ◽  
Cardiac Dysrhythmias ◽  
Cord Injury

The purpose of this study is to evaluate chronic spinal cord injury (SCI) patients for the incidence of cardiac dysrhythmias and the level of autonomic nervous system (ANS) dysfunction using 24-hour Holter recordings and long-term time-domain and frequency-domain heart rate variability (HRV) analysis. There was no difference be tween groups for the frequency of ventricular or supraventricular ectopics, minimal and mean heart rate, and the longest RR intervals. Maximum heart rate was lower in the quadriplegic group compared with controls (124.1 ± 11.2 vs. 139.4 ± 10.9, p < 0.05). Frequency-domain spectral analysis of high, low, total frequency powers, and ratio LF/HF showed no significant difference between groups. On time-domain analy sis SDANN (94.5 ± 26.4 vs. 131.1 ± 15.1, p < 0.0 1) and SDNN (110.1 ± 29.2 vs. 143.6 ± 19. 1, p < 0.05) were significantly lower in quadriplegics compared with controls. SDANN (74.0 ± 17.9 vs. 115.0 ± 14.2 p < 0.01) and SDNN ( 90.2 ± 21.1 vs. 130.0 ± 22.0 p < 0.05) were significantly lower in complete quadriplegics com pared with incomplete quadriplegics. When the effect of wake (07-22)-sleep (23-07) cycle on frequency-domain parameters were assessed, HF (12.38 ± 5.1 vs. 21.18 ± 8.05, p = 0.001) and TP (35.93 ± 10.5 vs. 45.68 ± 12.68, p = 0.004) showed the physiologic increase during sleep in controls, but was unchanged in quadriplegics (10.48 ± 5.39 vs. 13.35 ± 8.03, p = 0.205 and 30.67 ± 10.61 vs. 37.01 ± 17.59, p = 0.208, respectively). In paraplegics a blunted increase in HF (14.61 ± 7.69 vs. 19.85 ± 14.13, p = 0.09) and TP (38.5 ± 12.77 vs. 47.13 ± 23.08, p = 0.08) was observed. LF showed no significant change in the three groups. Heart rate circadian rhythm was preserved in all three groups (p < 0.01). We concluded that chronic complete cer vical SCI may disrupt modulatory sympathetic flow and downregulates parasympa thetic activity but causes no major arrhythmias needing treatment. Key Words: Chronic spinal cord injury—Cardiac dysrhythmia—Autonomic dysfunction-Heart rate variability.

scholarly journals Effects of Respiratory Training on Heart Rate Variability and Baroreflex Sensitivity in Individuals With Chronic Spinal Cord Injury

2018 ◽  
Vol 99 (3) ◽  
pp. 423-432 ◽  
Author(s):  
Bonnie E. Legg Ditterline ◽  
Sevda C. Aslan ◽  
David C. Randall ◽  
Susan J. Harkema ◽  
Camilo Castillo ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Heart Rate ◽  
Spinal Cord Injury ◽  
Heart Rate Variability ◽  
Baroreflex Sensitivity ◽  
Chronic Spinal Cord Injury ◽  
Cord Injury ◽  
Respiratory Training

Assessment of Autonomic Dysfunction in Chronic Complete Spinal Cord Injury by Heart Rate Variability

2015 ◽  
Vol 26 (1) ◽  
pp. 11-16
Author(s):  
BP Navin ◽  
Amitava Dube
Keyword(s):  
Spinal Cord ◽  
Heart Rate ◽  
Spinal Cord Injury ◽  
Heart Rate Variability ◽  
Autonomic Dysfunction ◽  
Low Frequency ◽  
Heart Rate Variability Analysis ◽  
Postural Change ◽  
Cardiac Autonomic Dysfunction ◽  
Cord Injury

Abstract Objectives Non-invasive assessment of cardiac autonomic dysfunction in spinal cord injury (SCI) by means of heart rate variability analysis (HRV). Also, to assess the effect of postural change on neural outflow. Setting Rehabilitation research center, Sawai Man Singh Hospital, Jaipur. Participants 110 patients with SCI were screened, of whom, 12 patients aged between 20 and 30 years with chronic complete SCI and neurological level of T6 or above were included. An equal number of age and sex matched healthy individuals were the controls. Interventions Five minute ECG recording, first in supine position and then in sitting position was done. Outcome measures Frequency domain measures of heart rate variability. Results No significant differences were observed between both the groups in supine rest. On sitting, the absolute power of the low frequency (LF) and high frequency (HF) components were significantly less in the SCI patients than that in the controls. A significantly increased LF-to-HF ratio along with a higher mean heart rate (HR) was observed in the controls on postural change. Conclusion On change of posture, the controls showed a physiologically patterned response, which was not observed in the SCI patients. The loss of this homeostatic mechanism in the SCI subjects was observed, which may reflect a dysfunctional autonomic nervous system interplay in patients with complete SCI.

scholarly journals The effect of level of injury and physical activity on heart rate variability following spinal cord injury

2017 ◽  
Vol 42 (2) ◽  
pp. 212-219 ◽  
Author(s):  
Athanasios Kyriakides ◽  
Dimitrios Poulikakos ◽  
Angeliki Galata ◽  
Dimitrios Konstantinou ◽  
Elias Panagiotopoulos ◽  
...  
Keyword(s):  
Physical Activity ◽  
Spinal Cord ◽  
Heart Rate ◽  
Spinal Cord Injury ◽  
Heart Rate Variability ◽  
Cord Injury
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