Vinylphosphonium Salt Mediated Efficient Synthesis of Dialkyl 1H-Pyrrolizine-2,3-dicarboxylates
Keyword(s):
Protonation of the 1:1 intermediate produced in the reaction between triphenylphosphine and dialkyl acetylenedicarboxylates by pyrrole-2-carbaldehyde leads to a vinylphosphonium salt, which undergoes intramolecular Wittig reaction to produce the title compounds in good yields.
1993 ◽
Vol 58
(17)
◽
pp. 4564-4566
◽