scholarly journals Live cell evaluation of granzyme delivery and death receptor signaling in tumor cells targeted by human natural killer cells

Blood ◽  
2015 ◽  
Vol 126 (8) ◽  
pp. e1-e10 ◽  
Author(s):  
Alexandra C. Vrazo ◽  
Adrianne E. Hontz ◽  
Sarah K. Figueira ◽  
Braeden L. Butler ◽  
Julie M. Ferrell ◽  
...  
Keyword(s):  
Natural Killer Cells ◽  
Natural Killer ◽  
Killer Cell ◽  
Death Receptor ◽  
Target Cells ◽  
Caspase Activation ◽  
Killer Cells ◽  
Human Natural Killer Cells ◽  
Death Receptor Signaling ◽  
Receptor Ligation

Key Points Natural killer cell granzyme B, A, and K delivery and subsequent caspase activation is rapid after conjugation with tumor target cells. Natural killer cells also induce caspase activation through death receptor ligation that can be monitored in real time.

NKG2-C is a receptor on human natural killer cells that recognizes structures on K562 target cells

1995 ◽  
Vol 25 (10) ◽  
pp. 2923-2931 ◽  
Author(s):  
Markus Düchler ◽  
Martin Offterdinger ◽  
Harry Holzmüller ◽  
Joachim Lipp ◽  
Chien-Ts Chu ◽  
...  
Keyword(s):  
Natural Killer Cells ◽  
Natural Killer ◽  
Target Cells ◽  
Killer Cells ◽  
Human Natural Killer Cells

Activity of human natural killer cells against target cells differing in sensitivity to interferon

1990 ◽  
Vol 110 (4) ◽  
pp. 1397-1400
Author(s):  
S. B. Cheknev ◽  
A. N. Narovlyanskii ◽  
A. M. Amchenkova ◽  
A. M. Sorokin ◽  
Ya. E. Khesin ◽  
...  
Keyword(s):  
Natural Killer Cells ◽  
Natural Killer ◽  
Target Cells ◽  
Killer Cells ◽  
Human Natural Killer Cells

scholarly journals NCR1 Expression Identifies Canine Natural Killer Cell Subsets with Phenotypic Similarity to Human Natural Killer Cells

2016 ◽  
Vol 7 ◽  
Author(s):  
Jennifer A. Foltz ◽  
Srinivas S. Somanchi ◽  
Yanwen Yang ◽  
Arianexys Aquino-Lopez ◽  
Erin E. Bishop ◽  
...  
Keyword(s):  
Natural Killer Cells ◽  
Natural Killer Cell ◽  
Natural Killer ◽  
Killer Cell ◽  
Killer Cells ◽  
Phenotypic Similarity ◽  
Human Natural Killer Cells

scholarly journals Single-cell analysis of the dynamics and functional outcomes of interactions between human natural killer cells and target cells

2012 ◽  
Vol 4 (10) ◽  
pp. 1175 ◽  
Author(s):  
Yvonne J. Yamanaka ◽  
Christoph T. Berger ◽  
Magdalena Sips ◽  
Patrick C. Cheney ◽  
Galit Alter ◽  
...  
Keyword(s):  
Natural Killer Cells ◽  
Single Cell ◽  
Natural Killer ◽  
Functional Outcomes ◽  
Single Cell Analysis ◽  
Target Cells ◽  
Cell Analysis ◽  
Killer Cells ◽  
Human Natural Killer Cells
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