scholarly journals An exploratory trial of insulin initiation and titration among patients with type 2 diabetes in the primary care setting with retrospective continuous glucose monitoring as an adjunct: INITIATION study protocol

2014 ◽  
Vol 15 (1) ◽  
Author(s):  
Irene D Blackberry ◽  
John S Furler ◽  
Louise E Ginnivan ◽  
Hanan Derraz ◽  
Alicia Jenkins ◽  
...  
2019 ◽  
Vol 7 (3) ◽  
pp. e000031
Author(s):  
In Wong

BackgroundIn the primary care setting in Macau, type 2 diabetes mellitus (T2DM) is the seventh most common reason for consultation. Inadequate glycaemic control constitutes a major public health problem and is associated with premature death and disability and decreased quality of life. Moreover, this condition substantially increases healthcare expenditures.ObjectiveThe primary objective was to assess the successful glycaemic control rates, blood pressure (BP) and cholesterol control rates in patients with T2DM in a Macau primary care setting. The secondary objective of this study was to assess the delay of insulin initiation in the Sao Lourence Health Center.MethodsPatients were stratified according to age (<65 years vs ≥65 years) and sex. Successful glycaemic control was defined as glycated haemoglobin (HbA1c) <7%. Successful cholesterol control was defined as a low-density lipoprotein cholesterol (LDL-C) level <2.6 mmol/L, and BP control was defined as BP <140/90 mm Hg.ResultsAmong the 2157 participants included in this study, 1046 (48.5%) patients had HbA1c <7%, 1209 (56.1%) patients had BP <140/90 mm Hg and 1244 (57.7%) patients had LDL-C <2.6 mmol/L. In conclusion, only 403 (18.7%) patients met the targets for all three measures. Of the 235 patients who were on insulin therapy, the mean (±SD) duration from T2DM diagnosis to insulin initiation was 7.47±6.52 years, the mean (±SD) duration from HbA1c not meeting the target (HbA1c ≥7% over 1 year and persistently) to insulin initiation was 3.34±3.66 years and the mean baseline HbA1c was 9.13%. Compared with patients with a longer duration (≥5 years) of HbA1c not meeting the target before insulin initiation, those who started insulin within 1 year of HbA1c not meeting the target had a better glycaemic control rate (40.7% vs 13%).ConclusionsNearly half of the patients at Sao Lourence Health Center, a primary care centre in Macau, met the glycaemic control target, but less than one-fifth of patients met all three targets for T2DM control. Moreover, there was a delay in insulin initiation for people with T2DM.


Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 102-LB
Author(s):  
JOHN FURLER ◽  
DAVID N. O’NEAL ◽  
JANE SPEIGHT ◽  
JO-ANNE E. MANSKI-NANKERVIS ◽  
SHARMALA THURAISINGAM ◽  
...  

2013 ◽  
Vol 37 ◽  
pp. S39
Author(s):  
Keith Bowering ◽  
Stewart Harris ◽  
Lawrence A. Leiter ◽  
Vincent Woo ◽  
Jean-François Yale

2003 ◽  
Vol 29 (4) ◽  
pp. 673-681 ◽  
Author(s):  
Hllarea Amthauer ◽  
Bridget Gagilo ◽  
Russell E. Glasgow ◽  
Wendy Dortch ◽  
Diane K. King

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