scholarly journals Radiotherapy-related changes in serum proteome patterns of head and neck cancer patients; the effect of low and medium doses of radiation delivered to large volumes of normal tissue

2013 ◽  
Vol 11 (1) ◽  
pp. 299 ◽  
Author(s):  
Piotr Widłak ◽  
Monika Pietrowska ◽  
Joanna Polańska ◽  
Tomasz Rutkowski ◽  
Karol Jelonek ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Normal Tissue ◽  
Serum Proteome

Normal Tissue Complications and Protection in Head and Neck Cancer Patients

2016 ◽  
pp. 753-767
Author(s):  
Andy Trotti ◽  
Nikhil Rao ◽  
Avraham Eisbruch ◽  
David I. Rosenthal
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Normal Tissue

EP-1817: Radiotherapy-related changes in serum proteome patterns of head and neck cancer patients

2014 ◽  
Vol 111 ◽  
pp. S295
Author(s):  
P. Widlak ◽  
M. Pietrowska ◽  
J. Polanska ◽  
K. Jelonek ◽  
I. Dominczyk ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Serum Proteome

Value of the Hospital Anxiety and Depression Scale in the follow up of head and neck cancer patients

2013 ◽  
Vol 127 (3) ◽  
pp. 285-294 ◽  
Author(s):  
L A Joseph ◽  
J A Routledge ◽  
M P Burns ◽  
R Swindell ◽  
A J Sykes ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Late Effects ◽  
Normal Tissue ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Hospital Anxiety ◽  
Scale Scores

AbstractBackground:Few studies have prospectively investigated psychological morbidity in UK head and neck cancer patients. This study aimed to explore changes in psychological symptoms over time, and associations with patients' tumour and treatment characteristics, including toxicity.Methods:Two hundred and twenty patients were recruited to complete the Hospital Anxiety and Depression Scale and the Late Effects on Normal Tissue (Subjective, Objective, Management and Analytic) (‘LENT-SOMA’) questionnaires, both pre- and post-treatment.Results:Anxiety was highest pre-treatment (38 per cent) and depressive symptoms peaked at the end of treatment (44 per cent). Anxiety significantly decreased and depression significantly increased, comparing pre- versus post-treatment responses (p < 0.001). Hospital Anxiety and Depression Scale scores were significantly correlated with toxicity, age and chemotherapy (p < 0.01 for all).Conclusion:This is the first study to analyse the relationship between Hospital Anxiety and Depression Scale scores and toxicity scores in head and neck cancer patients. It lends support for the use of the Hospital Anxiety and Depression Scale and the Late Effects on Normal Tissue (Subjective, Objective, Management and Analytic) questionnaire in routine clinical practice; furthermore, continued surveillance is required at multiple measurement points.

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