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A Phase I/III, multicenter, open-label trial of talimogene laherparepvec (T-VEC) in combination with pembrolizumab for the treatment of unresected, stage IIIb-IV melanoma (MASTERKEY-265)
Journal for ImmunoTherapy of Cancer
◽
10.1186/2051-1426-3-s2-p181
◽
2015
◽
Vol 3
(S2)
◽
Cited By ~ 14
Author(s):
Georgina V Long
◽
Reinhard Dummer
◽
Antoni Ribas
◽
Igor Puzanov
◽
Olivier Michielin
◽
...
Keyword(s):
Phase I
◽
Stage Iiib
◽
Talimogene Laherparepvec
◽
Open Label
◽
Open Label Trial
Download Full-text
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Cited By
References
Early safety from a phase I, multicenter, open-label, dose de-escalation study of talimogene laherparepvec (T-VEC) in Japanese patients (pts) with unresectable stage IIIB-IV melanoma (MEL)
Annals of Oncology
◽
10.1093/annonc/mdy439.007
◽
2018
◽
Vol 29
◽
pp. ix107
Author(s):
N. Yamazaki
◽
H. Koga
◽
T. Kojima
◽
A. Tsutsumida
◽
K. Namikawa
◽
...
Keyword(s):
Phase I
◽
Japanese Patients
◽
Stage Iiib
◽
Talimogene Laherparepvec
◽
Open Label
◽
Unresectable Stage
◽
Label Dose
Download Full-text
A Phase I, multicenter, open-label trial to evaluate the safety of talimogene laherparepvec (T-VEC) injected into liver tumors
Journal for ImmunoTherapy of Cancer
◽
10.1186/2051-1426-3-s2-p180
◽
2015
◽
Vol 3
(S2)
◽
Cited By ~ 3
Author(s):
J Randolph Hecht
◽
Steven Raman
◽
Daniel Y Sze
◽
A Craig Lockhart
◽
Rebecca A Moss
◽
...
Keyword(s):
Phase I
◽
Liver Tumors
◽
Talimogene Laherparepvec
◽
Open Label
◽
Open Label Trial
Download Full-text
A multicenter, open-label trial of talimogene laherparepvec (T-VEC) plus pembrolizumab vs pembrolizumab monotherapy in previously untreated, unresected, stage IIIB-IV melanoma.
Journal of Clinical Oncology
◽
10.1200/jco.2015.33.15_suppl.tps9081
◽
2015
◽
Vol 33
(15_suppl)
◽
pp. TPS9081-TPS9081
◽
Cited By ~ 7
Author(s):
Antoni Ribas
◽
Igor Puzanov
◽
Thomas Gajewski
◽
Georgina V. Long
◽
Reinhard Dummer
◽
...
Keyword(s):
Stage Iiib
◽
Talimogene Laherparepvec
◽
Open Label
◽
Open Label Trial
Download Full-text
Phase 2, multicenter, randomized, open-label trial assessing efficacy and safety of talimogene laherparepvec (T-VEC) neoadjuvant treatment (tx) plus surgery vs surgery for resectable stage IIIB/C and IVM1a melanoma (MEL).
Journal of Clinical Oncology
◽
10.1200/jco.2015.33.15_suppl.tps9094
◽
2015
◽
Vol 33
(15_suppl)
◽
pp. TPS9094-TPS9094
◽
Cited By ~ 6
Author(s):
Robert Hans Ingemar Andtbacka
◽
Michael Chastain
◽
Ai Li
◽
Mark Shilkrut
◽
Merrick I. Ross
Keyword(s):
Neoadjuvant Treatment
◽
Stage Iiib
◽
Phase 2
◽
Efficacy And Safety
◽
Talimogene Laherparepvec
◽
Open Label
◽
Open Label Trial
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Phase 1 results of a phase 1b/2, multicenter, open-label trial to evaluate safety and efficacy of talimogene laherparepvec (T-VEC) and ipilimumab (ipi) vs ipi alone in previously untreated, unresected stage IIIB-IV melanoma
Journal for ImmunoTherapy of Cancer
◽
10.1186/2051-1426-1-s1-p84
◽
2013
◽
Vol 1
(S1)
◽
Cited By ~ 4
Author(s):
Igor Puzanov
◽
Mohammed Milhem
◽
Robert Andtbacka
◽
David Minor
◽
Omid Hamid
◽
...
Keyword(s):
Phase 1
◽
Stage Iiib
◽
Talimogene Laherparepvec
◽
Open Label
◽
Safety And Efficacy
◽
Phase 1B
◽
Open Label Trial
Download Full-text
A Phase 1B/2, Multicenter, Open Label Trial to Evaluate the Safety and Efficacy of Talimogene Laherparepvec (T-Vec) and Ipilimumab (Ipi) Versus Ipi Alone in Previously Untreated, Unresected, Stage Iiib, Iiic, and Iv Melanoma
Annals of Oncology
◽
10.1093/annonc/mdu344.45
◽
2014
◽
Vol 25
◽
pp. iv391
◽
Cited By ~ 1
Author(s):
F.A. Collichio
◽
M. Milhem
◽
R.H. Andtbacka
◽
I. Puzanov
◽
Y. Saenger
◽
...
Keyword(s):
Stage Iiib
◽
Talimogene Laherparepvec
◽
Open Label
◽
Safety And Efficacy
◽
Phase 1B
◽
Open Label Trial
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Primary 2-year (yr) results of a phase II, multicenter, randomized, open-label trial of efficacy and safety for talimogene laherparepvec (T-VEC) neoadjuvant (neo) treatment (tx) plus surgery (surg) vs surg in patients (pts) with resectable stage IIIB-IVM1a melanoma
Annals of Oncology
◽
10.1093/annonc/mdz394.063
◽
2019
◽
Vol 30
◽
pp. v903
◽
Cited By ~ 2
Author(s):
R. Dummer
◽
D.E. Gyorki
◽
J. Hyngstrom
◽
A. Berger
◽
R. Conry
◽
...
Keyword(s):
Phase Ii
◽
Stage Iiib
◽
Efficacy And Safety
◽
Talimogene Laherparepvec
◽
Open Label
◽
Open Label Trial
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Abstract B13: A phase 2, randomized, open-label trial assessing efficacy and safety of talimogene laherparepvec (T-VEC) neoadjuvant treatment (tx) plus surgery vs. surgery for resectable stage IIIB-IVM1a melanoma
10.1158/1538-7445.mel2014-b13
◽
2015
◽
Cited By ~ 1
Author(s):
Robert HI Andtbacka
◽
Mohamed Shabooti
◽
Ai Li
◽
Michael Chastain
◽
Mark Shilkrut
Keyword(s):
Neoadjuvant Treatment
◽
Stage Iiib
◽
Phase 2
◽
Efficacy And Safety
◽
Talimogene Laherparepvec
◽
Open Label
◽
Open Label Trial
Download Full-text
A Phase I, Open-Label Trial to Assess the Absorption, Metabolism, and Excretion of (14C)-OPC-61815 in Healthy Male Japanese Subjects
Case Medical Research
◽
10.31525/ct1-nct04182958
◽
2019
◽
Author(s):
Keyword(s):
Phase I
◽
Healthy Male
◽
Open Label
◽
Open Label Trial
◽
Japanese Subjects
Download Full-text
Interim safety and efficacy of a randomized (1:1), open-label phase 2 study of talimogene laherparepvec (T) and ipilimumab (I) vs I alone in unresected, stage IIIB-IV melanoma
Annals of Oncology
◽
10.1093/annonc/mdw379.04
◽
2016
◽
Vol 27
◽
pp. vi380
◽
Cited By ~ 10
Author(s):
J. Chesney
◽
F. Collichio
◽
R.H.I. Andtbacka
◽
I. Puzanov
◽
J. Glaspy
◽
...
Keyword(s):
Stage Iiib
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Phase 2
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Talimogene Laherparepvec
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Open Label
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Safety And Efficacy
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Phase 2 Study
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Open Label Phase
Download Full-text
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