scholarly journals Interrelated modulation of endothelial function in Behcet's disease by clinical activity and corticosteroid treatment

2007 ◽  
Vol 9 (5) ◽  
pp. R90 ◽  
Author(s):  
Athanase D Protogerou ◽  
Petros P Sfikakis ◽  
Kimon S Stamatelopoulos ◽  
Christos Papamichael ◽  
Kostas Aznaouridis ◽  
...  
Keyword(s):  
Endothelial Function ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Corticosteroid Treatment ◽  
Clinical Activity ◽  
Behcet's Disease

FRI0442 Acute Phase Reactants and their Correlation with Clinical Activity in Behcet's Disease

2014 ◽  
Vol 73 (Suppl 2) ◽  
pp. 547.1-547
Author(s):  
B. Toz ◽  
N. Alpay-Kanitez ◽  
B. Erer ◽  
N. Polat ◽  
S. Kamali ◽  
...  
Keyword(s):  
Behçet’S Disease ◽  
Acute Phase ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Clinical Activity ◽  
Acute Phase Reactants ◽  
Behcet's Disease

Vascular endothelial function and plasma homocysteine levels in Behcet's disease

2004 ◽  
Vol 94 (4) ◽  
pp. 522-525 ◽  
Author(s):  
Ramazan Ozdemir ◽  
Irfan Barutcu ◽  
Alpay T. Sezgin ◽  
Nusret Acikgoz ◽  
Necip Ermis ◽  
...  
Keyword(s):  
Endothelial Function ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Plasma Homocysteine ◽  
Vascular Endothelial ◽  
Vascular Endothelial Function ◽  
Behcet's Disease

scholarly journals Circulated Activated Platelets and Increased Platelet Reactivity in Patients With Behçet’s Disease

2006 ◽  
Vol 12 (4) ◽  
pp. 451-457 ◽  
Author(s):  
Servet Akar ◽  
Mehmet Ali Özcan ◽  
Halil Ateş ◽  
Oğuz Gürler ◽  
Inci Alacacioglu ◽  
...  
Keyword(s):  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Platelet Reactivity ◽  
Control Group ◽  
Clinical Activity ◽  
Platelet Activity ◽  
Behcet's Disease ◽  
Control Subjects ◽  
Activated Platelets

Behçet’s disease (BD) is a multisystem disorder. Venous as well as arterial thrombosis is a common complication of BD but exact pathogenetic mechanism of the thrombotic tendency is not well known. This study aimed to evaluate circulating activated platelets and platelet reactivity in Behçet’s patients. Twenty-two Behçet’s patients (4 female, 18 male; mean age 38.6 ± 10.9 years) and 20 control subjects (8 female, 12 male; mean age 38.8 ± 9.4 years) were included. Those patients who had hypertension, hyperlipidemia, peripheral or coronary artery disease, hepatic or renal function abnormality, and who were using aspirin and other platelet-active drugs were excluded. Platelet activity and reactivity to adenosine diphosphate (ADP) were measured by whole blood flow cytometry. We assessed markers of platelet degranulation (P-selectin; CD62P) and the activated glycoprotein IIb/IIIa receptor (PAC1 binding to fibrinogen binding site) before and after stimulation with ADP. Platelet P-selectin expression was not significantly different between patients and control subjects both at baseline (p=0.420) and after stimulation (p=0.56). Baseline (p=0.001) and ADP-stimulated (p=0.003) PAC1 binding was significantly higher in Behçet’s patients than in the control group. Clinical activity has no effect on P-selectin expression and PAC1 binding. There is evidence of platelet activity and hyperreactivity in patients with BD and this may contribute to a prothrombotic state. In addition to aspirin, other antiplatelet drugs may be useful in the prevention and treatment of thrombosis in Behçet’s patients.

Crosstalk between inflammation, iron metabolism and endothelial function in Behçet's disease

2014 ◽  
Vol 56 (2) ◽  
pp. 175-185 ◽  
Author(s):  
Rita Oliveira ◽  
Patricia Napoleão ◽  
João Banha ◽  
Eleonora Paixão ◽  
Andreia Bettencourt ◽  
...  
Keyword(s):  
Endothelial Function ◽  
Behçet’S Disease ◽  
Iron Metabolism ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Behcet's Disease

Impaired haemostatic kinetics and endothelial function in Behçet's disease

1996 ◽  
Vol 240 (4) ◽  
pp. 181-187 ◽  
Author(s):  
İ. C. HAZNEDAROGILU ◽  
O. İ ÖZCEBE ◽  
O. ÖZDEMIR ◽  
İ. ÇELIK ◽  
S. V. DÜNDAR ◽  
...  
Keyword(s):  
Endothelial Function ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Behcet's Disease
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