scholarly journals Bovine Leukocyte Adhesion Deficiency in Danish Holstein-Friesian Cattle

1993 ◽  
Vol 34 (3) ◽  
pp. 231-236
Author(s):  
C.B. Jørgensen ◽  
J.S. Agerholm ◽  
J. Pedersen ◽  
P.D. Thomsen
1999 ◽  
Vol 47 (3) ◽  
pp. 283-289 ◽  
Author(s):  
Ágnes Jánosa ◽  
J. Dohy ◽  
B. Baranyai

'Bovine Leukocyte Adhesion Deficiency' (BLAD) is a recessive monofactorial, lethal inheritable defect occurring in Holstein-Friesian cattle and often passed on by well-known top bulls. The aim of this study was to find a relationship between the BLAD genotype of bulls, their genetic evaluation for milk and their daughters' milk production. BLAD-carrier and healthy bulls were compared on the basis of their breeding value published in November 1997. The first 100 bulls ranked according to the Total Production Index (TPI) were used, including nine BLAD carriers with 2,835 daughters and 77 healthy sires with 21,950 female progenies. For 14 bulls the BLAD genotype was not indicated. The healthy animals significantly outperformed the BLAD carriers, which result contradicts our earlier findings (Dohy et al., 1996; Jánosa and Dohy, 1997). In a BLAD elimination programme, the identification of BLAD carriers and properly planned mating are of great importance in order to avoid'inter se'mating of BLAD-carrier top animals which can be of significant influence in Holstein breeding.


1993 ◽  
Vol 34 (3) ◽  
pp. 237-243 ◽  
Author(s):  
J. S. Agerholm ◽  
H. Houe ◽  
C. B. Jørgensen ◽  
A. Basse

2021 ◽  
Vol 19 (3) ◽  
pp. 15-22
Author(s):  
Marta Gozdek ◽  
◽  
Magdalena Kolenda ◽  
Dariusz Kamola ◽  
Beata Sitkowska ◽  
...  

BLAD (bovine leukocyte adhesion deficiency) and DUMPS (deficiency of uridine monophosphate synthase) are hereditary lethal autosomal recessive disorders that may affect Holstein cattle. The aim of the present study was to evaluate the frequency of BLAD and DUMPS genotypes in the Polish population of dairy cows. In the study 5 732 Polish Holstein-Friesian females were genetically tested for BLAD and DUMPS. Results of the present study indicate that the Polish population of dairy cattle is free from DUMPS as there were not carriers nor sick animals. For BLAD the study confirmed the present of carriers in the population to be at a low value (0.21%). Both BLAD and DUMPS may strongly affect the profitability of a dairy farm, therefore, in order to avoid the economic losses caused by the presence of these genetic disorders in the herd it is important to screen the population and detect carriers as soon as possible.


2021 ◽  
Vol 185 ◽  
pp. 106133
Author(s):  
William Andrew ◽  
Jing Gao ◽  
Siobhan Mullan ◽  
Neill Campbell ◽  
Andrew W. Dowsey ◽  
...  

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