Ear (endolymphatic) duct blockage as a treatment for unmanageable Meniere’s disease

2021 ◽  
Author(s):  
Annejet Schenck
1981 ◽  
Vol 90 (6) ◽  
pp. 619-623 ◽  
Author(s):  
Robert A. Jahrsdoerfer ◽  
Wayne S. Cail ◽  
Robert W. Cantrell

Herniation of the jugular bulb into the middle ear is uncommon. Extension of a jugular bulb diverticulum into the petrous pyramid is rare. In ten previously reported cases in the literature, only the radiographic appearance of the lesion was stressed. Of interest to otolaryngologists is the fact that in seven of the cases there was an ipsilateral sensorineural hearing loss. Other symptoms included tinnitus and vertigo. One patient had been diagnosed as having Menière's disease. We document an additional case (a patient who had “classical Menière's disease”) and report the first known surgical exploration of this venous anomaly. The diverticulum extended high into the petrous bone and was found to obliterate the distal segment of the endolymphatic duct. To our knowledge, this is the first time that a cause and effect relationship has been recognized between endolymphatic hydrops and a jugular bulb diverticulum. We propose that the diverticulum, by obstructing the endolymphatic duct, was directly responsible for the Menière's-like symptoms.


1980 ◽  
Vol 89 (6_suppl2) ◽  
pp. 23-32 ◽  
Author(s):  
Juan-Carlos M. Antunez ◽  
Fred H. Linthicum ◽  
Frank R. Galey ◽  
Gilbert D. McCann

The anatomy of the human endolymphatic duct system of three cases — one with Menière's syndrome (with no histopathological evidence of endolymphatic hydrops), one with Menière's disease (with histopathological evidence of endolymphatic hydrops), and one with no evidence of disease — has been studied by means of computer-aided and graphic reconstruction from serial sections of temporal bones. The reconstructions have revealed a canalicular arrangement of the epithelial lining of the rugose portion of the human endolymphatic sac. Accordingly, new nomenclature, “pars canalicularis,” is suggested for this portion. The computer produced lateral and medial views of the endolymphatic duct and sac of the patient with Menière's syndrome. The computer also calculated the luminal volume, the surface area of the epithelium, and the surface-to-volume ratio of the rugose portion of the sac. In addition, the authors graphically reconstructed the rugose portion of the sac of all three cases. Measurements of the dimensions of these reconstructions were made, from which the luminal volume was estimated. The reconstructed images and the calculations allowed quantitative comparison of the microscopic anatomy of the rugose portion of the sac in the Menière's syndrome and Menière's disease ears with that in an ear without evidence of disease. Significant differences were found in the volumes of the rugose portion of the sac of the three cases. The results suggest that the luminal volume of the rugose portion of the sac of Menière's disease patients may be significantly reduced. The authors speculate that endolymphatic hydrops may be the result of a loss of epithelial surface area in the canalicular portion, thus diminishing its resorptive function. The computer and graphic reconstruction techniques in conjunction with their analytical capabilities provide a new method for studying inner ear structures. These techniques have the potential to expand the capabilities of quantitative morphology and provide the means for deriving clinically useful data from histopathological and ultrastructural material.


ORL ◽  
1985 ◽  
Vol 47 (6) ◽  
pp. 288-293 ◽  
Author(s):  
Fitzgerald O’Connor ◽  
D. Bagger-Sjöbäck ◽  
U. Friberg ◽  
H. Rask-Andersen

1981 ◽  
Vol 74 (3) ◽  
pp. 183-189 ◽  
Author(s):  
Andrew W Morrison

The otological practice at The London Hospital provides very large numbers of patients with Ménière's disease from a busy department. This clinical material has been utilized as much as possible, without research assistants or funds, to examine some clinical and pathological aspects of the disease which might have a bearing on aetiology. The investigation procedures which are likely to lead to an earlier and more certain diagnosis are outlined and prognostic indicators are mentioned. It would appear that there may be an hereditary predisposition to progressive idiopathic endolymphatic hydrops. Potential sufferers tend to have migraine, a family history of migraine, minor degrees of basilar impression associated with an abnormally located endolymphatic duct and sac, a more emotional personality, and possibly an association with blood group A. The experimental and clinicopathological evidence supports the view that the endolymphatic duct and sac have an important role in the pathogenesis of both idiopathic and secondary hydrops. Ultrastructural examination is continuing and may shed more light on the pathology at a cellular level. There is, as yet, no cure for Ménière's disease and sufferers will be incapacitated in varying degrees, often severely, for the rest of their days.


2021 ◽  
Vol 11 ◽  
Author(s):  
Jun He ◽  
Anquan Peng ◽  
Junjiao Hu ◽  
Zhiwen Zhang ◽  
Yichao Chen ◽  
...  

Objective: The purpose of the present study was to evaluate the dynamics of endolymphatic hydrops (EH) and symptoms in a group of patients who underwent endolymphatic duct blockage (EDB) for treatment of intractable Meniere's Disease (MD), and to explore a metric for verifying the effectiveness of EDB procedure.Methods: A total of 22 patients with intractable MD patients who underwent EDB participated in the present study. EH was visualized using locally enhanced inner ear magnetic resonance imaging (MRI) prior to and following surgery. The vestibular hydrops ratio (VHR) in the second MRI examination was compared with the pre-surgery recordings.Results: Following EDB, 6 patients exhibited complete or partial reversal of EH, complete control of vertigo spells and reported improvement in hearing; 13 patients showed no changes in EH or hearing, but 5 of these patients exhibited complete control of vertigo attacks, and the other 8 patients exhibited improved control of vertigo attacks. The final 3 patients showed an increase in EH, but symptomatic worsening in 2 patients, and symptomatic improvement in 1 patient. There was a significant difference in the average VHR prior to and following EDB. Postoperative VHR was positively correlated with the frequency of vertigo spells in the latest 6 months of follow-up and improvement of postoperative average hearing threshold.Conclusion: The decreased EH accompanying the reduction in vertigo attacks and hearing preservation may provide a metric for verifying the effectiveness of EDB treatment in patients with MD.


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