scholarly journals Value of T1 mapping on gadoxetic acid-enhanced MRI for microvascular invasion of hepatocellular carcinoma: a retrospective study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Chenyi Rao ◽  
Xinquan Wang ◽  
Minda Li ◽  
Guofeng Zhou ◽  
Hongmei Gu
Keyword(s):  
Hepatocellular Carcinoma ◽  
Retrospective Study ◽  
T1 Mapping ◽  
Microvascular Invasion ◽  
Gadoxetic Acid ◽  
Enhanced Mri

scholarly journals Value of T1 Mapping on Gadoxetic acid-enhanced MRI for Microvascular Invasion of Hepatocellular Carcinoma: A Retrospective Study

2020 ◽  
Author(s):  
chenyi Rao ◽  
Xinquan Wang ◽  
Minda Li ◽  
Guofeng Zhou ◽  
Hongmei Gu
Keyword(s):  
Hepatocellular Carcinoma ◽  
Relaxation Time ◽  
T1 Mapping ◽  
Operating Characteristic ◽  
Reduction Rate ◽  
Gadoxetic Acid ◽  
T1 Relaxation Time ◽  
T1 Relaxation ◽  
Enhanced Mri ◽  
Adc Values

Abstract Background: To evaluate the utility of non-invasive parameters driving from T1 mapping on gadoxetic acid-enhanced MRI for predicting microvascular invasion (MVI) of hepatocellular carcinoma (HCC) compared with diffusion-weighted imaging (DWI).Methods: A total of 94 patients with single HCC undergoing partial hepatectomy was included in the retrospective study, who underwent preoperative gadoxetic acid-enhanced MRI combined with DWI and T1 mapping. Parameters including precontrast, postcontrast and reduction rate of T1 relaxation time and ADC values were measured for differentiating MVI-positive HCCs (n=38) from MVI-negative HCCs (n=56). The receiver operating characteristic curve (ROC) was analyzed to compare the diagnostic performance of the calculated parameters.Results: The mean value of postcontrast T1 relaxation time were significantly higher in MVI-positive HCCs that MVI-negative HCCs (621.0 vs. 536.5, P <0.001). MVI-positive HCCs demonstrated significantly lower reduction rates of T1 relaxation time and lower ADC values than MVI-negative HCCs (39.4% vs 49.9, P<0.001; 1.495×10-3mm2/s vs 1.620×10-3mm2/s, P=0.003, respectively). The area under receiver operating characteristic curves were 0.587, 0.728, 0.824 and 0.690 for precontrast, postcontrast, reduction rate of T1 relaxation time and ADC, respectively. The reduction rate of T1 relaxation time was the most reliable feature with sensitivity, specificity and accuracy of the cut-off value (44.9%) of 79.0%, 73.2%, 75.5%, respectively.Conclusions: Reduction rate of T1 relaxation time on gadoxetic acid-enhanced MRI holds promise for evaluating MVI status of HCC.

Preoperative gadoxetic acid–enhanced MRI for predicting microvascular invasion in patients with single hepatocellular carcinoma

2017 ◽  
Vol 67 (3) ◽  
pp. 526-534 ◽  
Author(s):  
Sunyoung Lee ◽  
Seong Hyun Kim ◽  
Ji Eun Lee ◽  
Dong Hyun Sinn ◽  
Cheol Keun Park
Keyword(s):  
Hepatocellular Carcinoma ◽  
Microvascular Invasion ◽  
Gadoxetic Acid ◽  
Enhanced Mri

scholarly journals Gadoxetic Acid–enhanced MRI of Hepatocellular Carcinoma: Value of Washout in Transitional and Hepatobiliary Phases

Radiology ◽  
2019 ◽  
Vol 291 (3) ◽  
pp. 651-657 ◽  
Author(s):  
Dong Hwan Kim ◽  
Sang Hyun Choi ◽  
So Yeon Kim ◽  
Min-Ju Kim ◽  
Seung Soo Lee ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Gadoxetic Acid ◽  
Enhanced Mri
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